Sütçü İneklerde Kistik Ovaryumların GnrH Ve Aynı Anda Uygulanan GnrH-pgf2 ile Sagıtımı
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Dosyalar
Tarih
2002
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Selçuk Üniversitesi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Özet: Sunulan çalışmada, ovaryum kistlerinin sağitiminda GnRH hormonu ve aynı anda uygulanan GnRH-PGF2xx kom- binasyonunun etkisi araştırıldı. Çalışmanın materyalini postpartum 45-150. günler arasında bulunan Holstein irka 270 baş inek- ten rektal palpasyon ve ultrasonografik muayene yöntemleriyle ovaryum kisti tanısı konulan 14 baş inek oluşturdu. İşletmede bulunan 270 baş inek, önce dölverimi kayıtlan ve klinik semptomlar da gözönünde bulundurularak rektal palpasyon ile mu- ayene edildi. İlk muayenede ovaryum kisti şüphesi bulunan 14 baş ineğe 10 gün sonra ikinci kez rektal palpasyon uygulandi. On gün ara ile tekrarlanan rektal muayene uygulamalanından hemen sonra inelder, real-time ultrason ile muayene edildi. Rek- tal palpasyon ve ultrasonografik muayene yöntemlerine göre ovaryum kisti tespit edilen ineklerden, yapılacak sağıtımın et kinliğinin ve kist tipinin belirlenmesi amacıyla enjeksiyon günü (0. gün) ve daha sonra 3, 7 ve 14 günlerde kan alındı. Alınan kan ömeklerinden plazmalar aynlarak, plazma progesteron düzeyleri belirlendi. Sağıtım uygulamaları amacıyla ovaryum kisti tanisi konulan 14 baş inek random yöntemiyle 7'şer başlık 2 gruba ayrıldı. Birinci gruptaki ineklerin 7'sine 20 ug buserelin (GnRH), 7'sine de 20 ug buserelin-25 mg dinoprost (PGF20) kombinasyonu kas içi yolla enjekte edildi. Her iki grupta bu- lunan ineklerin % 71.4'ü sağitima cevap verdi ve gebe kaldı. GnRH ve GnRH-PGF2a gruplanında sağitim-ik ostrús aralığ sırasıyla 16.4:2.75 ve 11.4 plus/minus 2.75 gün sağitim-gebe kalma aralığı 53:9.43 ve 58.8:19 15 gün olarak elde edildi ve istatistik fark bulunmadı. Her iki grupta gebelik başına yapılan tohumlama sayısı ise 1.4 olarak bulundu. Sonuç olarak, ovaryum kist lerinin sağitiminda aynı anda uygulanan GnRH-PGF20 kombinasyonuyla sağlanan sağitim-ilk östrüs ve sağitim-gebe kalma aralıklarının sadece GnRH uygulamasına göre önemli bir avantaj oluşturmadığı ve aynı anda uygulanan GnRH ve PGF2a'nın birbirinin etkisini olumsuz olarak etkilemediği tespit edildi. Ayrica plazma progesteron düzeyinin belirlenmesinin de uygulama sonrası sağıtımın izlenmesi bakımından çok önemli olduğu kanısına varıldı.
Summary: In this study, the effects of GnRH, and combination of GnRH and PGF20 hormones were investigated in the tre- atment of ovarian cysts. Fourteen Holstein cows in postpartum having ovarian cysts on the days of 45-150 were selected by rectal palpation and ultrasonography from 270 Holstein cows. The cows with ovarian cysts were subjected to 2 rectal pal- pations 10 days apart. Following this ultrasonographic examinations were performed. In addition to these, plasma pro- gesterone levels were also determined for detecting the effectiveness of treatment which would provide differential diagnosis of cysts at the time of injection day (0) and thereafter at days 3, 7 and 14. Fourteen cows with cystic ovaries were divided into two groups in equal numbers for the treatment. Twenty ug buserelin (GnRH) were injected to the group 1, and 20 µg buserelin (GnRH) and 25 mg dinoprost (PGF2a) to the group II. 71.4 % of the cows were responded to the treatment and become preg nant in both groups. The time interval between the treatment-first estrous in the group I and II were 16.4 + 2.75 and 11.4:2.75 days (P>0.05), and the time interval between the treatment-conception were 53 + 9.43 and 58.8 + 19.15 days ( P > 0.051 res- pectively Average number of inseminations required per conception in both groups of animals was 1.4. As a result, the pre- sent study suggests that treatment of ovarian cysts with simultaneous GnRH and PGF2u were not significant compared to GnRH alone based on the findings of concerning about treatment-first estrous and treatment-conception intervals. It was found that simultaneous GnRH and PGF2a treatment had no effect to alter the effects of each drug. In addition to these, de- termining the plasma progesteron levels was found useful for evaluation of the effectiveness of the treatment.
Summary: In this study, the effects of GnRH, and combination of GnRH and PGF20 hormones were investigated in the tre- atment of ovarian cysts. Fourteen Holstein cows in postpartum having ovarian cysts on the days of 45-150 were selected by rectal palpation and ultrasonography from 270 Holstein cows. The cows with ovarian cysts were subjected to 2 rectal pal- pations 10 days apart. Following this ultrasonographic examinations were performed. In addition to these, plasma pro- gesterone levels were also determined for detecting the effectiveness of treatment which would provide differential diagnosis of cysts at the time of injection day (0) and thereafter at days 3, 7 and 14. Fourteen cows with cystic ovaries were divided into two groups in equal numbers for the treatment. Twenty ug buserelin (GnRH) were injected to the group 1, and 20 µg buserelin (GnRH) and 25 mg dinoprost (PGF2a) to the group II. 71.4 % of the cows were responded to the treatment and become preg nant in both groups. The time interval between the treatment-first estrous in the group I and II were 16.4 + 2.75 and 11.4:2.75 days (P>0.05), and the time interval between the treatment-conception were 53 + 9.43 and 58.8 + 19.15 days ( P > 0.051 res- pectively Average number of inseminations required per conception in both groups of animals was 1.4. As a result, the pre- sent study suggests that treatment of ovarian cysts with simultaneous GnRH and PGF2u were not significant compared to GnRH alone based on the findings of concerning about treatment-first estrous and treatment-conception intervals. It was found that simultaneous GnRH and PGF2a treatment had no effect to alter the effects of each drug. In addition to these, de- termining the plasma progesteron levels was found useful for evaluation of the effectiveness of the treatment.
Açıklama
Anahtar Kelimeler
Ovaryum Kisti, GnRH, PGF2a, İnek, Ovarian Cysts, Cows
Kaynak
Eurasian Journal of Veterinary Sciences
WoS Q Değeri
Scopus Q Değeri
Cilt
18
Sayı
3-4
Künye
Erdem, H., Tekeli, T., Uçar, M., Yenice, M., (2002). Sütçü İneklerde Kistik Ovaryumların GnrH Ve Aynı Anda Uygulanan GnrH-pgf2 ile Sagıtımı. Eurasian Journal of Veterinary Sciences, 18(3-4), 57-61.
