Cytokeratin 18 and h-FABP levels in intestinal ischemiareperfusion injury: Role of coenzyme Q10

Basit Öğe Kaydı
dc.contributor.authorBelviranlı, Muaz
dc.contributor.authorOkudan, Nilsel
dc.contributor.authorGökbel, Hakkı
dc.contributor.authorKıyıcı, Aysel
dc.contributor.authorÖz, Mehmet
dc.contributor.authorKumak, Ayşe
dc.date.accessioned2020-03-26T18:40:55Z
dc.date.available2020-03-26T18:40:55Z
dc.date.issued2013
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractAim: The objective of this study was to investigate whether coenzyme Q10 (CoQ10) supplementation affects M30 and heart-type fatty acid binding protein (h-FABP) levels in intestinal ischemiareperfusion injury-induced rats. Materials and methods: Thirty-two male Wistar rats were randomly divided into 4 groups. 1) Sham: Animals exposed to laparotomy without clamping the superior mesenteric artery (SMA); 2) ischemiareperfusion (IR): rats exposed to laparotomy with occlusion of the SMA for 45 min, followed by 120 min of reperfusion period; 3) CoQ10 plus sham: 10 mg kg body weight 1 CoQ10 was administrated via intraperitoneal injection for 20 days, and thereafter animals were exposed to laparotomy without clamping the SMA; 4) CoQ10 plus IR: 10 mg kg body weight 1 CoQ10 was administrated via intraperitoneal injection for 20 days and thereafter animals were exposed to laparotomy with occlusion of the SMA for 45 min, followed by 120 min of reperfusion period. Blood samples were taken by cardiac puncture for the analysis of serum h-FABP and M30 levels. Results: There was no difference among the groups for serum h-FABP and M30 antigen levels. Conclusion: Neither intestinal ischemiareperfusion injury nor CoQ10 supplementation affect serum h-FABP and M30 levels in rats.en_US
dc.identifier.endpage11en_US
dc.identifier.issn1300-0144en_US
dc.identifier.issn1303-6165en_US
dc.identifier.issue1en_US
dc.identifier.startpage6en_US
dc.identifier.urihttp://www.trdizin.gov.tr/publication/paper/detail/TVRRd09EUTRPQT09
dc.identifier.urihttps://hdl.handle.net/20.500.12395/29087
dc.identifier.volume43en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofTurkish Journal of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectCerrahien_US
dc.titleCytokeratin 18 and h-FABP levels in intestinal ischemiareperfusion injury: Role of coenzyme Q10en_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

TR-Dizin İndeksli Yayınlar Koleksiyonu