Prevention of Postoperative Nausea-Vomiting in Children: Comparison of Granisetron and Droperidol Plus Metoclopramide

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dc.contributor.authorÇelik, J.
dc.contributor.authorReisli, R.
dc.contributor.authorTuncer, S.
dc.contributor.authorDuman, A.
dc.contributor.authorÖkeşli, S.
dc.date.accessioned2020-03-26T16:37:36Z
dc.date.available2020-03-26T16:37:36Z
dc.date.issued2001
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThis study was performed to compare the efficacy of a droperidol-metoclopramide combination with granisetron to prevent postoperative nausea and vomiting after tonsillectomy with or without adenoidectomy in children. Ninety pediatric patients, ASA class I, aged 4-10 years, were enrolled in a prospective, randomized, double-blind investigation and assigned to one of two treatment regimens; granisetron 40 mg/kg (Group G, n=45), droperidol 50 mg/kg plus metoclopramide 0.25 mg/kg (Group DM, n=45). Antiemetic drugs were administered intravenaously (IV) after inhaled induction of general anaesthesia. The same standard general anesthetic technique was used. Tracheal extubation was performed while patients were still deeply anaesthetized. Acetaminophen (10-25 mg/kg PR) was applied for postoperative analgesia to all children. The rate of complete response, defined as no emesis and no need for rescue antiemetics, 0-3 h after anaesthesia were 85% in group G, 87% in group DM (p>0.05). No clinically important adverse events were observed in any of the groups.en_US
dc.identifier.citationÇelik, J., Reisli, R., Tuncer, S., Duman, A., Ökeşli, S., (2001). Prevention of Postoperative Nausea-Vomiting in Children: Comparison of Granisetron and Droperidol Plus Metoclopramide. Turk Anesteziyoloji ve Reanimasyon, 29(3), 135-139.
dc.identifier.endpage139en_US
dc.identifier.issn1016-5150en_US
dc.identifier.issue3en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage135en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/17660
dc.identifier.volume29en_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorÇelik, J.
dc.institutionauthorReisli, R.
dc.institutionauthorTuncer, S.
dc.institutionauthorDuman, A.
dc.institutionauthorÖkeşli, S.
dc.language.isotren_US
dc.relation.ispartofTurk Anesteziyoloji ve Reanimasyonen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectDroperidolen_US
dc.subjectGranisetronen_US
dc.subjectMetoclopramideen_US
dc.subjectNauseaen_US
dc.subjectPediatric anaesthesiaen_US
dc.subjectTonsillectomyen_US
dc.subjectVomitingen_US
dc.titlePrevention of Postoperative Nausea-Vomiting in Children: Comparison of Granisetron and Droperidol Plus Metoclopramideen_US
dc.title.alternativeÇocuklarda Postoperatif Bulantı-Kusmanın Önlenmesinde Granisetron İle Droperidol ve Metoklopramid Kombinasyonunun Karşılaştırılmasıen_US
dc.typeArticleen_US

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