The relationship of metabolic syndrome, serum leptin levels and treatment in bipolar disorder [İkiuçlu bozuklukta metabolik sendrom, serum leptin düzeyleri ve tedavi i?lişkisi]
Küçük Resim Yok
Tarih
2008
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Objective: In this study we aimed to evaluate the association between serum leptin levels and metabolic syndrome in bipolar patients Method: Sixty bipolar I disorder (BD) patients, of 29 under mood stabilizer (MS) (lithium, valproic acid, carbamazepin and lamotrigine) treatment and of 31, under atypical antipsychotics (AA) (risperidone, quetiapine and olanzapine) treatment for at least 3 months were enrolled. Metabolic syndrome (MetS) was screened according to NCEP ATP III (Adult Treatment Protocol of the National Cholesterol Education Programme) criteria. Results: 36.7% of the patients were MetS. The AA subgroup had significantly more MetS than MS. Abdominal obesity was significantly correlated with leptin levels in BD. There was not found significant association between MetS and leptin levels in BD. Discussion: AA taking bipolar patients had higher MetS rates. However, there was no significant difference among AAs for MetS prevelance. Leptin levels were significantly correlated with abdominal obesity in bipolar patients but seem not to be associated with MetS.
Açıklama
Anahtar Kelimeler
Atypical antipsychotics, Bipolar disorder, Leptin, Metabolic syndrome
Kaynak
Klinik Psikofarmakoloji Bulteni
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
18
Sayı
2
