Gebelerde hepatit B virusu infeksiyonu sıklığı ve bebeğe vertikal geçişin araştırılması
Küçük Resim Yok
Tarih
1997
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Bu çalışmada Hepatit B Virüsü (HBV) infeksiyonunun gebelerdeki sıklığı ve bebeğe geçiş oranı araştırıldı. 327gebe çalışmaya alındı. HBsAg 8 gebede (%2.4), anti-HBs ve anti-HBc IgG 79 (%24.1) gebede pozitif bulundu. HBsAg pozitif bulunan 8 gebede ayrıca HBeAg, anti-HBc IgM ve anti-HBe araştırıldı. HBeAg, anti-HBc IgM hepsinde negatif bulundu, anti-HBe ise 5 (%62.5) hastada pozitif, 3 (%37.5) hastada negatif bulundu. HBsAg taşıyıcısı gebelerde, bebeğe geçiş olup olmadığını araştırmak amacıyla kordon kanında HBsAg, HBeAg ve anti-HBe bakıldı. İki (%25.0) bebekte HBsAg pozitif bulunurken, HBeAg hepsinde negatif, anti-HBe ise hepsinde pozitif olarak tesbit edildi. Bu çalışmada HBV ınfeksiyonu ile operasyon anamnezi, öğrenim düzeyi ve parite arasında istatistiksel olarak anlamlı bir fark saptanamadı. Kan transfüzyonu yapılmış olanlardaki HBV ile karşılaşma oranı, transfüzyon yapümamışlardaki orandan fazla bulundu ve aradaki fark istatistiksel olarak anlamlı idi. Diş çekim ve tedavisi gören gebelerde HBV ile karşılaşma oranı, diş çekim ve tedavisi görmemiş olanlar dan.fazla idi ve aradaki fark istatistiksel olarak anlamlı idi.
In this study, the prevalance of hepatitis B virus(HBV) infection in pregnancy and transmis¬sion rate to the newborn were investigated. Three hundred and twenty seven pregnant women were included in our study. The possible risk factors were determined for each patient. HBsAg was positive in 8 (2.4%), anti-HBs and anti-HBc IgG were positive in 79 (24.1%) pregnant women. In addition, HBeAg, anti-HBc IgM and anti-HBe were investigated in 8 HBsAg positive pregnant women Anti-HBe was positive in 5 (62.5%) and negative in 3 (37.5%) pregnant women. In HBsAg earner pregnant women HBsAg, HBeAg and anti-HBe were studied in cord blood samples to evaluate the transmission to the newborn. HBsAg was positive in two (25%) babies and HBeAg was negative and anti-HBe was positive in all blood samples. In this study, a statistically significant relation between HBV infection and operation history, education levels and parity of the pregnancy was not established. In pregnant women who rece¬ived blood transfusion, the HBV exposure rate was higher than the women who did not receive any transfusion, and the difference was statistically significant. In pregnant women who had dental interventions, the HBV exposure rate was higher than who did not and the difference was statistically significant.
In this study, the prevalance of hepatitis B virus(HBV) infection in pregnancy and transmis¬sion rate to the newborn were investigated. Three hundred and twenty seven pregnant women were included in our study. The possible risk factors were determined for each patient. HBsAg was positive in 8 (2.4%), anti-HBs and anti-HBc IgG were positive in 79 (24.1%) pregnant women. In addition, HBeAg, anti-HBc IgM and anti-HBe were investigated in 8 HBsAg positive pregnant women Anti-HBe was positive in 5 (62.5%) and negative in 3 (37.5%) pregnant women. In HBsAg earner pregnant women HBsAg, HBeAg and anti-HBe were studied in cord blood samples to evaluate the transmission to the newborn. HBsAg was positive in two (25%) babies and HBeAg was negative and anti-HBe was positive in all blood samples. In this study, a statistically significant relation between HBV infection and operation history, education levels and parity of the pregnancy was not established. In pregnant women who rece¬ived blood transfusion, the HBV exposure rate was higher than the women who did not receive any transfusion, and the difference was statistically significant. In pregnant women who had dental interventions, the HBV exposure rate was higher than who did not and the difference was statistically significant.
Açıklama
Anahtar Kelimeler
Genel ve Dahili Tıp
Kaynak
İç Hastalıkları Dergisi (:Dahili Tıp Bilimleri Dergisi )
WoS Q Değeri
Scopus Q Değeri
Cilt
4
Sayı
5
