Investigation of viral pathogens during pregnancy in a city region in Turkey [Türki?ye'ni?n bi?r şehri?nde gebeli?k sirasinda vi?ral patojenleri?n araştirilmasi]
Küçük Resim Yok
Tarih
2011
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Rubella virus, Cytomegalovirus (CMV) and Herpes simplex virus (HSV)-II are the infectious agents which may cause congenital malformations in the fetus if acquired during pregnancy. Thus these agents must be screened throughout pregnancy. This screening is also important to demonstrate the regional status regarding these agents. In this study; it is aimed to evaluate the seroprevalance of Rubella, CMV and HSV-II in pregnant women in a city region in Turkey. A total of 249 pregnant women who applied to the outpatient clinics of the obstetric and gynaecological department of a university hospital were involved to the study during antenatal screening in the first trimester of pregnancy. After separation of blood sample sera samples were tested for antibodies to Rubella, CMV and HSV-II. While Rubella and CMV antibodies were tested using Enzyme Linked Floeresan Antibody method, HSV-II was tested using ELISA. The mean age of the participants in this study was 28.4± 3.4 years. The seropositivity for anti-Rubella IgM, anti-Rubella IgG, anti-CMV IgM, anti-CMV IgG, anti-HSV-II IgM, and anti-HSV-II IgG were 0.4%, 95.9%, 0%, 98.7%, 0%, 4.4%, respectively. Although the seropositivity of HSV-II was very low, seropositivities of Rubella and CMV were very high in our area of investigation. Viruses causing congenital infection and malformation must be screened in pregnant women individually and avidity tests must be applied in suspicious cases. In addition the seroprevelance of these viral infections should be known in every population in order to take preventive measures and prepare local and general health policies.
Açıklama
Anahtar Kelimeler
Cytomegalovirus, Herpes simplex, Pregnancy, Rubella antibody
Kaynak
Anatolian Journal of Clinical Investigation
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
5
Sayı
2
