Akut Gastroenteritli 0-5 yaş arası çocuklarda viral etkenlerin sıklığının araştırılması
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Tarih
2016
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Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Viral gastroenteritler, çocukluk çağında görülen gastroenteritlerin en sık nedenidir. Başlıca enterik virüsler; rotavirüsler, enterik adenovirüsler, astrovirüsler, nörovirüsler ve sapovirüsleri içeren kalisivirüslerdir. Çeşitli ülkelerde yapılan son çalışmalarda nörovirüsler, çocukluk çağı gastroenteritlerinde önemli bir enterik patojen olarak belirlendi. Ancak nörovirüs enfeksiyonlarının epidemiyolojik özellikleri ve hastalık yükü bilinmemektedir. Çalışmanın amacı viral gastroenteritlerde nörovirüs sıklığını belirlemektir. Gereç ve Yöntemler: Kasım 2011-Aralık 2012 tarihleri arasında ishal atağı ile pediatri polikliniğine ayaktan başvuran 96 hastanın gaita örnekleri analiz edildi. Gaita örneklerinde, rotavirüs, enterik adenovirüs ve nörovirüs immünokromatografik yöntemle araştırıldı. Akut gastroenteritli 1-60 ay arası çocuklar çalışmaya dahil edildi. İshal atağının şiddeti 'Vesikari' skoru kullanılarak belirlendi. Bulgular: Hastalardan alınan 96 gaita örneğinin 53'ünde viral antijen tespit edildi. Rotavirüs %39.6, adenovirüs %10,4, nörovirüs %5.2, oranında tespit edildi. Hastaların ortalama yaşı 20,414,5 aydı. Çalışmada, gastroenteritle ilişkili semptomlardan kusma %77.1, ateş %50, karın ağrısı %24, bulantı %18.8 oranında bulundu. Kusma, rotavirüs pozitif hastalarda %92.1 oranında tespit edildi, istatiksel olarak anlamlı bulundu (p0.005).Sonuç: 0-5 yaş arası akut gastroenteritli çocuklarda 6 ay süren çalışmada, nörovirüsler; rotavirüs ve enterik adenovirüslerden sonra üçüncü viral patojen olarak saptanmıştır
Objective: Viral gastroenteritis is the most frequent cause of gastroenteritis in childhood. The major enteric viruses are rotaviruses, enteric adenoviruses, astroviruses and human caliciviruses including noroviruses and sapoviruses. Recent surveys conducted in various countries have identified noroviruses as an important enteric pathogens in sporadic cases of gastroenteritis in childhood. However, the epidemiological features and disease load are unknown. The aim of this study was to determine the incidence of norovirus gastroenteritis among viral gastroenteritis cases. Material and Methods: Stool specimens of 96 cases who had presented to our pediatrics outpatient clinic between November 2011 and April 2012 due to diarrhea were analyzed. Rotavirus, enteric adenovirus and norovirus were searched for in stool specimens using the immunochromatographic method. Patients with acute gastroenteritis between the ages of 1-60 months were included in the study. The severity of gastroenteritis was assessed by using the Vesicari scale. Results: Viral antigens were determined in 53 of the 96 stool specimens. Rotaviruses were identified in 39.6%, adenoviruses in 10.4%, and noroviruses in 5.2%. The mean age on admission was 20.414.5 months. The clinical symptoms associated with viral gastroenteritis in this study were vomiting (77.1%), fever (50%), abdominal cramps (24%), and nausea (18.8%). Vomiting was identified in 92.1% of rotavirus positive patients and this was statistically significant (p0.005). Conclusion: During the study period of six months, norovirus has determined as third viral pathogen after rotavirus and adenovirus with gastroenteritis in children 0-5 age group
Objective: Viral gastroenteritis is the most frequent cause of gastroenteritis in childhood. The major enteric viruses are rotaviruses, enteric adenoviruses, astroviruses and human caliciviruses including noroviruses and sapoviruses. Recent surveys conducted in various countries have identified noroviruses as an important enteric pathogens in sporadic cases of gastroenteritis in childhood. However, the epidemiological features and disease load are unknown. The aim of this study was to determine the incidence of norovirus gastroenteritis among viral gastroenteritis cases. Material and Methods: Stool specimens of 96 cases who had presented to our pediatrics outpatient clinic between November 2011 and April 2012 due to diarrhea were analyzed. Rotavirus, enteric adenovirus and norovirus were searched for in stool specimens using the immunochromatographic method. Patients with acute gastroenteritis between the ages of 1-60 months were included in the study. The severity of gastroenteritis was assessed by using the Vesicari scale. Results: Viral antigens were determined in 53 of the 96 stool specimens. Rotaviruses were identified in 39.6%, adenoviruses in 10.4%, and noroviruses in 5.2%. The mean age on admission was 20.414.5 months. The clinical symptoms associated with viral gastroenteritis in this study were vomiting (77.1%), fever (50%), abdominal cramps (24%), and nausea (18.8%). Vomiting was identified in 92.1% of rotavirus positive patients and this was statistically significant (p0.005). Conclusion: During the study period of six months, norovirus has determined as third viral pathogen after rotavirus and adenovirus with gastroenteritis in children 0-5 age group
Açıklama
Anahtar Kelimeler
Pediatri
Kaynak
Türkiye Çocuk Hastalıkları Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
10
Sayı
2
Künye
Çelik, A. Y., Emiroğlu, M., Kurtoğlu, M. G., İnci, A., Odabaş, D. (2016). Akut Gastroenteritli 0-5 Yaş Arası Çocuklarda Viral Etkenlerin Sıklığının Araştırılması. Türkiye Çocuk Hastalıkları Dergisi, 10(2), 101-106.
