Response to Levetiracetam in a Patient With Posthypoxic Action Myoclonus
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Dosyalar
Tarih
2007
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Posthipoksik aksiyon miyoklonisi (PAM) hipoksik beyin hasarı sonrasında gelişebilir ve farmakolojik tedaviye dirençlidir. Sunulan hastada PAM sonucu oluşan çok ciddi miyoklonik sıçramalar hastayı tamamen işgöremez hale getirmiştir.Hastanın miyoklonileri velproat, topiramat, klonazepam ve baklofen gibi sık kullanılan tedavi ajanlarının tek başına ya da bir arada kullanımına yanıt vermemiştir, ancak levetirasetam başlandıktan sonra önemli ölçüde düzelme gözlenmiştir.
Posthypoxic action myoclonus (PAM) can be developed in patients who survived an hypoxic brain injury and is resistant to pharmacological therapy. The patient presented here developed PAM with very serious myoclonic jerks by which he was fully incapacitated. His myocloni did not respond to treatment with most commonly used agents, i.e. valproate, topiramate, clonazepam and baclofen alone or in combination. An important degree of improvement was observed after levetiracetam was started.
Posthypoxic action myoclonus (PAM) can be developed in patients who survived an hypoxic brain injury and is resistant to pharmacological therapy. The patient presented here developed PAM with very serious myoclonic jerks by which he was fully incapacitated. His myocloni did not respond to treatment with most commonly used agents, i.e. valproate, topiramate, clonazepam and baclofen alone or in combination. An important degree of improvement was observed after levetiracetam was started.
Açıklama
Anahtar Kelimeler
Nörolojik Bilimler, Posthypoxic action myoclonus, levetiracetam, Posthipoksik aksiyon myoklonusu, levetirasetam
Kaynak
Journal of Neurological Sciences (Turkish)
WoS Q Değeri
Scopus Q Değeri
Cilt
24
Sayı
3
Künye
Genç, E., Tokgöz, S., Doğan, A. E., Genç, B. O., (2007). Response to Levetiracetam in a Patient With Posthypoxic Action Myoclonus. Journal of Neurological Sciences (Turkish), 24(3), 250-253.
