Geçici iskemik atak ve akut istemik inmeli hastalarda hematolojik parametrelerin karşılaştırılması
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Tarih
2004
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Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Bu çalışmanın amacı geçici iskemik atak (GİA) ve akut iskemik inme (Aİİ) hastalarında bazı hematolojik parametreleri karşılaştırmak ve bu parametrelerdeki değişiklikleri saptamaktır. Yöntem: Akut serebral iskemi semptomlarıyla müracat eden hastaların nörolojik ve laboratuar değerlendirilmesi yapıldı. Tanısı kesinleşen 94 Aİİ’li ve 70 GİA’lı hasta çalışmaya alındı. Kontrol grubu nörolojik semptom ve bulgu vermeyen, değişik şikayetlerle acil servise müracat eden, yaş ve cinsiyet olarak uygun 72 hastadan oluştu. Serebral iskemi semptomlarının başlangıcından itibaren 72 saat içinde müracaat eden bütün hastalardan kabulden hemen sonra kan alındı. Alınan kan örneklerinden BK, Trombosit, fibrinojen, sedimantasyon değerleri saptandı ve elde edilen değerlerin gruplar arası karşılaştırılması yapıldı. Bulgular: Trombosit sayısı GİA ve Aİİ gruplarında kontrol grubuna göre yüksek olarak bulundu (p0,001). Fibrinojen seviyesi, lökosit sayısı ve sedimantasyon Aİİ’li hastalarda hem kontrol hem de GİA grubuna göre yüksekti (p0,001). Sonuç: Sonuçlarımız, bazı hematolojik parametrelerin (özellikle lökosit sayısı, fibrinojen ve sedimantasyon) spesifik olmamakla birlikte özellikle akut iskemik inmenin habercisi olabileceğini desteklemektedir.
Objective: The aim of the study was to determine the changes of hematologic parameters and compare these changes in patients with transient ischemic attack (TİA) and acute ischemic stroke (AIS). Methods: Neurologic and laboratory assessment of patients applying with the symptoms of acute cerebral ischemia to the emergency department was performed. Ninety four patients with AIS and seventy patients with TIA who became definite diagnosis, was included to the study. The cases without neurological symptoms and signs but with different complaints who have comparable age and sex were accepted as control group. The blood sample was taken in all patients who applied in 72 hours after the beginning of the symptoms of cerebral ischemia. The blood sample was analyzed and the value of white blood cell (WBC), thrombocyte, fibrinogen, sedimentation determined and these parameters were compared between groups. Results: The platelet number was found higher in TIA and AIS groups than control group (p<0,001). The fibrinogen value, white blood cell number and value of sedimentation was higher in patient with AIS than both TIA and control groups (p<0,001). Conclusion: This study results support that some hematological parameters such as WBC fibrinogen and sedimentation could be an indicator of acute cerebral ischemia although it is not specific.
Objective: The aim of the study was to determine the changes of hematologic parameters and compare these changes in patients with transient ischemic attack (TİA) and acute ischemic stroke (AIS). Methods: Neurologic and laboratory assessment of patients applying with the symptoms of acute cerebral ischemia to the emergency department was performed. Ninety four patients with AIS and seventy patients with TIA who became definite diagnosis, was included to the study. The cases without neurological symptoms and signs but with different complaints who have comparable age and sex were accepted as control group. The blood sample was taken in all patients who applied in 72 hours after the beginning of the symptoms of cerebral ischemia. The blood sample was analyzed and the value of white blood cell (WBC), thrombocyte, fibrinogen, sedimentation determined and these parameters were compared between groups. Results: The platelet number was found higher in TIA and AIS groups than control group (p<0,001). The fibrinogen value, white blood cell number and value of sedimentation was higher in patient with AIS than both TIA and control groups (p<0,001). Conclusion: This study results support that some hematological parameters such as WBC fibrinogen and sedimentation could be an indicator of acute cerebral ischemia although it is not specific.
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Genel ve Dahili Tıp
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Cilt
14
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2
