Çocuklarda Desfluran-Sevofluran Anestezisinin İdame ve Derlenme Üzerine Olan Etkilerinin Karşılaştırılması
Küçük Resim Yok
Tarih
2003
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Bu çalışmada çocuklarda kısa süreli cerrahi girişimlerde anestezi idamesinde kullanılan desfluran ve sevofluranın özellikleri karşılaştırıldı. Yaşları 4-12 olan 50 çocuk çalışmaya alındı. Anestezi indüksiyonundan 30 dk önce 0.5 mg kg-1 midazolam oral uygulandı. Anestezi indüksiyonu için 2-2.5 µg kg-1 propofol, 10 µg kg-1 alfentanil ve 0.1 mg kg-1 sisatrakuryum verildikten sonra hastalar randomize olarak iki gruba ayrıldı ve anestezi idamesi için % 60 N2O ile birlikte % 6-7 desfluran (grup I) ve 2-2.5 % sevofluran (grup II) uygulandı. Cerrahi başlamadan önce, hastalara postoperatif analjezi için 20 mg kg-1 parasetamol rektal uygulandı. Postoperataif bulantıkusma insidansını azaltmak için 150 µg kg-1 deksametazon verildi. Sistolik arter basıncı, diyastolik arter basıncı, ortalama arter basıncı ve kalp atım hızı indüksiyon öncesi, indüksiyon ve entübasyon sonrası, cerrahi başladıktan 5., 10. ve 20. dk. sonra ve anestezi sonunda kaydedildi. Anestezik ajanlar ameliyat bitiminde kesildi. Ekstübasyon ve derlenme zamanı kaydedildi. Ajitasyon üç puanlı skorlama ile değerlendirildi. Her iki grupta da hemodinamik parametreler bazal değerlerin % 30'unda seyretti. Derlenme zamanı desfluran grubunda daha kısa bulundu (p0.05). Ekstübasyon zamanı ve ajitasyon insidansı iki grupta benzer bulundu (p0.05). Her iki grupta postoperatif kusma insidansında istatistiksel olarak anlamlı farklılık bulunmadı (p0.05). Sonuç olarak çocuklarda propofol indüksiyonu sonrası desfluran ve sevofluranın anestezi idamesinde güvenle kullanılabileceği kanısındayız.
In this study, the characteristics of desflurane and sevoflurane were compared for maintenance of anaesthesia in short-term surgery of children. Fifty children, 4-12 years old were studied. Thirty minutes prior to the induction of anaesthesia, all patients received 0.5 mg kg-1 midazolam orally. They were randomly assigned to receive 6-7 % desfurane (group I) and 2-2.5 % sevoflurane (group II) with 60 % nitrous oxide in oxygen for maintenance of anaesthesia. For anaesthesia induction all patients were given 2-2.5 mg kg-1 propofol, 10 µg kg-1 alfentanil and 0.1 mg kg-1 cisatracurium and after two minutes all patients were intubated. Before surgery, patients received 20 mg kg-1 paracetamol rectally for postoperative analgesia. Dexamethasone 150 µg kg-1 was given to reduce the incidence of postoperative nausea and vomiting. Systolic arterial pressure, diastolic arterial pressure, mean arterial pressure and heat rate were measured: before induction, after induction and during intubation, 5, 10, 20 minutes afte r surgery and at the end of anaesthesia. At the end of the operation extubation and recovery times were determined. Agitation was evaluated by using the three point score. Hemodynamic parameters were satisfactorily maintained within ± 30 % of baseline values in both groups. Recovery time was significantly shorter in the desflurane group than sevoflurane group (p<0.05). Extubation time and incidence of agitation were similar for both groups. Differences in the incidence of postoperative vomiting were not statistically significant between the groups. As a result, we concluded that both sevoflurane and desflurane can be used safely for the maintenance of anaesthesia after induction of propofol in children.
In this study, the characteristics of desflurane and sevoflurane were compared for maintenance of anaesthesia in short-term surgery of children. Fifty children, 4-12 years old were studied. Thirty minutes prior to the induction of anaesthesia, all patients received 0.5 mg kg-1 midazolam orally. They were randomly assigned to receive 6-7 % desfurane (group I) and 2-2.5 % sevoflurane (group II) with 60 % nitrous oxide in oxygen for maintenance of anaesthesia. For anaesthesia induction all patients were given 2-2.5 mg kg-1 propofol, 10 µg kg-1 alfentanil and 0.1 mg kg-1 cisatracurium and after two minutes all patients were intubated. Before surgery, patients received 20 mg kg-1 paracetamol rectally for postoperative analgesia. Dexamethasone 150 µg kg-1 was given to reduce the incidence of postoperative nausea and vomiting. Systolic arterial pressure, diastolic arterial pressure, mean arterial pressure and heat rate were measured: before induction, after induction and during intubation, 5, 10, 20 minutes afte r surgery and at the end of anaesthesia. At the end of the operation extubation and recovery times were determined. Agitation was evaluated by using the three point score. Hemodynamic parameters were satisfactorily maintained within ± 30 % of baseline values in both groups. Recovery time was significantly shorter in the desflurane group than sevoflurane group (p<0.05). Extubation time and incidence of agitation were similar for both groups. Differences in the incidence of postoperative vomiting were not statistically significant between the groups. As a result, we concluded that both sevoflurane and desflurane can be used safely for the maintenance of anaesthesia after induction of propofol in children.
Açıklama
Anahtar Kelimeler
Cerrahi
Kaynak
Türk Anestezi ve Reanimasyon Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
31
Sayı
8
Künye
Uzun, S., Tuncer, S., Tavlan, A., Reisli, R., Sarkılar, G., Ökeşli, S., (2003). Çocuklarda Desfluran-Sevofluran Anestezisinin İdame ve Derlenme Üzerine Olan Etkilerinin Karşılaştırılması. Türk Anestezi ve Reanimasyon Dergisi, 31(8), 415-421.
