Sezaryen operasyonlarında intratekal bupivakain-morfin ve bupivakain-sufentanilin karşılaştırılması
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2004
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info:eu-repo/semantics/openAccess
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Amaç: Çalışmamızın amacı sezaryen operasyonlarında %0.5'lik bupivakainin tek başına yada intratekal sufentanil (5g) veya morfinle (200 g) kombinasyonunun duyusal ve motor blok özellikleri, hemodinamik değerler, neonatal prognoz ve yan etkiler bakımından değerlendirilmesiydi. Çalışmanın Yapıldığı yer: Selçuk Üniversitesi Meram Tıp Fakültesi. Materyal Metod: Bu çalışma randomize, prospektif ve çift kör olarak (n60, her grupta 20 hasta) planlandı. Üç grup, sadece %0.5'lik bupivakain, bupivakain ile beraber intratekal sufentanil (5g) ve bupivakain ile beraber morfinden (200 g) oluşmaktaydı. Bulgular: Kontrol grubunda, duyusal bloğun T{10} 'a yükselme zamanı ve motor bloğun başlama zamanı daha uzun (p0.05) ve duyusal bloğun T{10} 'a gerileme süresi diğer iki gruptan daha kısa idi (p0.05). Motor bloğun geri dönme zamanı morfin grubunda sufentanil ve kontrol grubuna göre daha uzun bulundu (p0.05). Postoperatif analjezi süresi kontrol grubunda sufentanil ve morfin grubuna göre daha kısa idi (p0.05) ve bu periyod morfin grubunda kontrol ve sufentanil grubuna göre belirgin olarak uzun bulundu (p0.05). Sonuç: Sezaryen operasyonlarında intratekal %0.5'lik bupivakaine (lOmg), sufentanil (5g) ve morfin (200g) eklenmesi yenidoğanda depresyon yapmaksızın ve annede hemodinamiği bozmadan yeterli ve uzun süreli analjezi süresi sağlamaktadır.
Objective: Our aim in the present study was to evaluate the effects 0.5% hyperbric bupivacaine alone, or combined with either intrathecal sufentanil (5g) or morphine (200 g), on sensory and motor block characteristics, hemodynamic variables, neonatal outcome and site effects in cesarean section. Institution: Selçuk University, Faculty of Meram Medicine. Material and Methods: This study was a randomized, prospective and double-blinded study (n60, 20 parturients per groups). Three groups were consisted of only 0.5% bupivacaine, bupivacaine combine with intrathecal sufentanil (5g) and bupivacaine combine with morphine (200g). Results: In control group, reaching T{10} dermatom of sensory block and the onset of motor block were statistically significantly longer (p<0.05) and times for T10 level regression of sensory block were shorter (p<0.05) than those in other 2 groups. Times for regression of motor block in morphine group was longer than compared with sufentanil and control group (p<0.05). Postoperative analgesia period was significantly shorter in control group than sufentanil and morphine groups (p<0.05) and significantly longer in morhine group than control and sufentanil group. Conclusion: In the cesarean sections addition of sufentanil (5 g) and morphine (200g) to 0.5% bupivacaine (lOmg) provides sufficient peroperative analgesia without depresing the baby and compromising the hemodynamics value of the mother and longers postoperative analgesia period.
Objective: Our aim in the present study was to evaluate the effects 0.5% hyperbric bupivacaine alone, or combined with either intrathecal sufentanil (5g) or morphine (200 g), on sensory and motor block characteristics, hemodynamic variables, neonatal outcome and site effects in cesarean section. Institution: Selçuk University, Faculty of Meram Medicine. Material and Methods: This study was a randomized, prospective and double-blinded study (n60, 20 parturients per groups). Three groups were consisted of only 0.5% bupivacaine, bupivacaine combine with intrathecal sufentanil (5g) and bupivacaine combine with morphine (200g). Results: In control group, reaching T{10} dermatom of sensory block and the onset of motor block were statistically significantly longer (p<0.05) and times for T10 level regression of sensory block were shorter (p<0.05) than those in other 2 groups. Times for regression of motor block in morphine group was longer than compared with sufentanil and control group (p<0.05). Postoperative analgesia period was significantly shorter in control group than sufentanil and morphine groups (p<0.05) and significantly longer in morhine group than control and sufentanil group. Conclusion: In the cesarean sections addition of sufentanil (5 g) and morphine (200g) to 0.5% bupivacaine (lOmg) provides sufficient peroperative analgesia without depresing the baby and compromising the hemodynamics value of the mother and longers postoperative analgesia period.
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