Investigation of Mutagenic Effects of Some Plant Growth Regulators on Salmonella/ Microsome Test System
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Dosyalar
Tarih
2010
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Parlar Scientific Publications (P S P)
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
In this study, beta-naphthoxyacetic acid (BNOA), 4-chlorophenoxyacetic acid (4-CPA) and 2,4-dichlorophenoxyacetic acid (2,4-D) used as plant growth regulators were investigated in order to determine their possible mutagenic activity by Salmonella/microsome test system. Non-toxic doses of BNOA (500, 100, 50, 10, 1 mu g/plaque), 4-CPA (200, 100, 50, 25, 10 mu g/plaque) and 2,4-D (100, 50, 10, 1, 0.1 mu g/plaque) were used in the assays. Assays were carried out through the Salmonella typhimurium TA 98 and TA 100 strains under the conditions both with and without metabolic activation (S9). Numbers of revertants determined in the assays performed with nontoxic doses were compared to those of control plates. Any significant increases in the number of revertants were not observed, in the presence or absence of metabolic activation (S9). Based on the results, it was concluded that BNOA, 4-CPA and 2,4-D were not found to be mutagenic or promutagenic in the Salmonella/microsome test system.
Açıklama
Anahtar Kelimeler
Mutagenicity, Salmonella typhimurium, Plant growth regulators, Salmonella / microsome test
Kaynak
Fresenius Environmental Bulletin
WoS Q Değeri
N/A
Scopus Q Değeri
Cilt
19
Sayı
10
Künye
Uysal, A., Durak, Y., Aladağ, M. O., (2010). Investigation of Mutagenic Effects of Some Plant Growth Regulators on Salmonella/ Microsome Test System. Fresenius Environmental Bulletin, 19(10), 2170-2175.