Optical coherence tomography findings in patients with Wolfram syndrome [Wolfram sendromlu hastalarda optik koherans tomografi bulgulari{dotless}]

Basit Öğe Kaydı
dc.contributor.authorKöktekir B.E.
dc.contributor.authorBakbak B.
dc.contributor.authorGönül Ş.
dc.contributor.authorGedik Ş.
dc.date.accessioned2020-03-26T18:58:53Z
dc.date.available2020-03-26T18:58:53Z
dc.date.issued2014
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjectives: To report the optical coherence tomography (OCT) fndings in patients with Wolfram syndrome. Materials and Methods: Four patients who fulfilled the criteria for Wolfram syndrome were recruited to the study. In all patients, OCT was performed with Stratus OCT (OCT-3, Carl Zeiss Meditec, Inc. Germany). The fast retinal nerve fiber layer (RNFL) and fast macular thickness protocols were used to measure the RNFL and macular thickness, respectively. The fast optic disc protocol was used to determine the cup-to-disc ratios of the optic disc. All patients were examined with VEP (Retimax, CSO Strumenti Oftalmici, Florence, Italy). Results: In eight eyes of four patients (3 male and 1 female) with a mean age of 18.5±2.08 years (range 16-21 years), RNFL, macular thickness, and cup-to-disc ratios were determined. The mean RNFL was 42.2±5.6 ?m (range 34.1-49.5 ?m), while the mean macular thickness and cup-to-disc ratios were 145±15 ?m (range 125-160 ?m) and 0.79±0.07 (range 0.7-0.92), respectively. There was a moderate negative correlation between VEP latencies and macular and RNFL thicknesses (Spearman correlation coefficient was -0.23 and -0.34, respectively). Conclusions: RNFL loss and secondary optical atrophy are severe complications that may affect the visual acuity in patients with Wolfram syndrome. Retinal changes in these patients may be quantified and can be observed using OCT.en_US
dc.identifier.doi10.4274/tjo.19327en_US
dc.identifier.endpage215en_US
dc.identifier.issn1300-0659en_US
dc.identifier.issue3en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage212en_US
dc.identifier.urihttps://dx.doi.org/10.4274/tjo.19327
dc.identifier.urihttps://hdl.handle.net/20.500.12395/31328
dc.identifier.volume44en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTurkish Ophthalmology Societyen_US
dc.relation.ispartofTurk Oftalmoloiji Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectDiabetes mellitusen_US
dc.subjectMacular thicknessen_US
dc.subjectOptic atrophyen_US
dc.subjectVisual lossen_US
dc.subjectWolfram syndromeen_US
dc.titleOptical coherence tomography findings in patients with Wolfram syndrome [Wolfram sendromlu hastalarda optik koherans tomografi bulgulari{dotless}]en_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu