Astımlı hastalarımızın klinik ve laboratuvar özellikleri ve bunları etkileyen etmenler
Küçük Resim Yok
Tarih
2006
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Astım tanısı ile izlediğimiz hastaların genel özellikleri ve risk faktörlerini belirlemek. Gereç ve Yöntem: Çocuk İmmünoloji ve Alerji BD tarafından Eylül 2001-Mart 2003 tarihleri arasında astım tanısı ile izlenen 486 hastanın klinik ve laboratuvar özellikleri değerlendirildi. Bulgular: Hastalar 5 yaş altı (grup-1, % 37) ve 5 yaş üstü (grup-2; % 63) olarak iki gruba ayrıldı. Atopi oranı grup-1'de %45 bulunurken grup-2'de %57 saptandı. Hastaların %80'i şehir merkezinde yaşıyordu. En sık başvuru yakınması öksürük (%64) olup belirtiler haştalann %76'sında 5 yaş altında başlamıştı. Ailede atopik hastalık öyküsü %40 hastada vardı. Ebeveynlerden en az birinin evde sigara içme oranı %49 iken evde hayvan besleme oranı %8 bulundu. Şehir-kırsal bölge arasında atopi yönünden fark yoktu. Ancak grup-1'de şehirde yaşayan hastalarda atopi oranı kırsal bölgeye göre yüksek bulundu. Grup-2 de polen duyarlılığı grup-1 'den anlamlı oranda yüksek bulundu. Diğer alerjenlere duyarlılık yönünden gruplar arası anlamlı fark yoktu, Epidermal deri testinde en az bir alerjene duyarlılık oranı %51 olup birden fazla alerjene duyarlılık % 24 oranında bulundu. Alerjen duyarlılığı en fazla ev tozu akarlanna (%51) ve polenlere (%5Ö) karşı saptandı. Astıma, hastaların %33'ünde alerjik rinit, %17'sinde atopik dermatit, %7'sinde adenoid hipertrofi, %8'inde gastroozefageal reflü eşlik ediyordu. Hastaların %48'inde serum total IgE yüksekliği, %24'ünde periferik kanda eozinofili vardı. Adenoid hipertrofisi atopik hastaların %10'unda vardı ve atopik olmayanlara göre iki kat fazla saptandı., Çıkarımlar: Bölgemizde atopi gelişimi yönünden için şehirde yaşam özellikle 5 yaş altı hastalarda önemli bir risk etmeni olarak görülmektedir. Polenlere karşı duyarlılık yaşla birlikte artmaktadır. Alerjen duyarlılık adenoid hipertrofisine katkıda bulunmaktadır.
Aim: To define the general features and the the risk factors of the children with bronchial asthma. Material and Method: The records of 486 patients, who were followed up in our Pediatric Immunology and Allergy Department with the diagnosis of bronchial asthma from September 2001 to March 2003, were investigated retrospectively. Results: Patients were divided into two groups according to their age; group I, patients under 5 years old age (63%), and group II, patients older than 5 years old age (37%). The frequency of atopy was 45% and 57% in groups, retrospectively. Eighty percent of the patients were living in the urban areas. The most common symptom was cough, and symptoms were begun within the first five years in 76% of the patients. Forty percent of the patients had a family history of atopy. Smoking of parents and the ratio of having domestic animals were noted in 49% and 8% of the cases, respectively. No significant difference was noted in terms of atopy in patients living in urban or rural area. However, a significant difference was noted in patients under the 5 years old age. Pollen allergy was common in the second group, but no significant difference was noted in other allergens. The frequency of atopy in patients was 51% and 24% at least to one allergen and more than one allergen, retrospectively. The most common allergen was hoüse-dust mite (51%) and pollens (50%), retrospectively. Asthma was associated with allergic rhinitis in 33%, atopic dermatitis in 17%, gastroesophageal reflux in 8% and adenoid hypertrophy in 7% of the cases. Forty-eight percentages of the cases had increased IgE levels and 24% of the cases had eosonophilia in periferic smears. Ten percentages of the atopic cases had adenoid hypertrophy and it was twice than non-atopic patients. Conclusions: In this study, we conclude that living in the urban area is an important risk factor for the development of atopy in our area. Pollen hypersensitivity is increasing with the age. Adenoid hypertrophy is important for the allergen sensitivity.
Aim: To define the general features and the the risk factors of the children with bronchial asthma. Material and Method: The records of 486 patients, who were followed up in our Pediatric Immunology and Allergy Department with the diagnosis of bronchial asthma from September 2001 to March 2003, were investigated retrospectively. Results: Patients were divided into two groups according to their age; group I, patients under 5 years old age (63%), and group II, patients older than 5 years old age (37%). The frequency of atopy was 45% and 57% in groups, retrospectively. Eighty percent of the patients were living in the urban areas. The most common symptom was cough, and symptoms were begun within the first five years in 76% of the patients. Forty percent of the patients had a family history of atopy. Smoking of parents and the ratio of having domestic animals were noted in 49% and 8% of the cases, respectively. No significant difference was noted in terms of atopy in patients living in urban or rural area. However, a significant difference was noted in patients under the 5 years old age. Pollen allergy was common in the second group, but no significant difference was noted in other allergens. The frequency of atopy in patients was 51% and 24% at least to one allergen and more than one allergen, retrospectively. The most common allergen was hoüse-dust mite (51%) and pollens (50%), retrospectively. Asthma was associated with allergic rhinitis in 33%, atopic dermatitis in 17%, gastroesophageal reflux in 8% and adenoid hypertrophy in 7% of the cases. Forty-eight percentages of the cases had increased IgE levels and 24% of the cases had eosonophilia in periferic smears. Ten percentages of the atopic cases had adenoid hypertrophy and it was twice than non-atopic patients. Conclusions: In this study, we conclude that living in the urban area is an important risk factor for the development of atopy in our area. Pollen hypersensitivity is increasing with the age. Adenoid hypertrophy is important for the allergen sensitivity.
Açıklama
Anahtar Kelimeler
Pediatri
Kaynak
Türk Pediatri Arşivi
WoS Q Değeri
Scopus Q Değeri
Cilt
41
Sayı
2
