Kuzularda Deneysel Oluşturulan Akut Solunum Si?stemi? Enfeksi?yonlarının Teşhi?si?nde Arteri?yal Kan Gazlarının Önemi?
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Dosyalar
Tarih
2005 Aralık
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Selçuk Üniversitesi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Bu araştırmada, kuzularda deneysel oluşturulan solunum sistemi enfeksiyonlarının teşhisinde arteriyal ve venöz kan gazlanının önemini belirlemek ve hangi parametrelerin hastalığın teşhisinde daha güvenilir olduğunu ortaya koymak amaçlanmıştır. Kuzular deneme (7 kuzu) ve kontrol (6 kuzu) grubu olmak üzere 2 gruba ayrıldı. Kuzulara Pastorella hemolitica (8x108 bakteri/ml), Klebsiella pnömoni (8x108 bakteri/ml) ve Parainfluenza 3 virus şuşları traka içi verilerek enfeksiyon oluşturuldu. Kontrol grubundaki kuzulardan bir kez arteriyal ve venöz kan örnekleri alınırken, deneme grubundaki kuzulardan enfeksiyonun 1., 2., 3. ve 4. günlerinde arteriyal ve venöz kan örnekleri alındı. Deneme grubu kuzuların WBC sayısı (p<0.001), beden isisi (p<0.001), kalp (p<0.01) ve solunum sayıları (p<0.001) kontrol grubuna göre önemli oranda yüksekti. Arteriyal kan gazlarında sadece pCO2'de farklılık (p<0.01) gözlenirken, venöz kan gazlarında pH (p<0.01), pCO2 (p<0.01), pO2(p<0.05) ve O2SAT (p<0.0 düzeylerinde kayda değer farklılık tespit edildi. Histopatolojik muayenede deneme grubu kuzuların akciğerlerinde intertisiyal ve apseli pnömoni gözlendi. Sonuç olarak, kuzuların akut akciğer enfeksiyonlarında arteriyal kan gazların çok fazla etkilenmediği ve çoğunlukla venöz kan gazlarının etkilendiği, bu yüzden hastalığın teşhisinde venöz kan gazlarının değerlendirilmesi ile daha sağlıklı sonuç alınabileceği kanısına varıldı.
The importance of arterial and venouse blood gas in the diagnosis of experimentally induced respiratory tract diseases in lambs and to the most reliable which parameters in the diagnosis of disaese were aimed to determine in this study. The lambs divided to control ( 6 lambs) and experimental ( 7 lambs) groups. Pasteurella haemolytica (8x108 CFU/ mi), Clebsiella pneumoniae (8x108 CFU/ml) and Paraenfluenza 3 viruse were inoculated by intratracheal for induced respiratory tract diseases in the lambs (experimental groups). Blood samples were taken from the femoral arteria and the jugular vein once in the control group of lambs. Blood samples were taken from the femoral arteria and the jugular vein on days 1th, 2th, 3th, and 4th of the infection in the experimental group of lambs. The WBC (p<0.001), body temperature (p<0.001), respiratory rate (p<0.001), and heart rate (p<0.01) were significantly increased in the experimental group of lambs compared with the control group of lambs pH (p<0.01). pCO2 (p<0.01), p02 (p<0.05), and oxygen saturation (p<0.05) in venouse blood were significantly different in the the experimental group of lambs compared with the control group of lambs. pCO2 (p<0.01) in arterial blood was significantly different in the the experimental group of lambs compared with the control group of lambs. In the histopathologic examination, interstitial pneumonia and pneumonia with abcessation was determined in the lung of experimental group of the lambs. The results of this study showed that, artenal blood gases did not influenced in acute respiratory enfection, but venouse blood gases did more influenced in acute res piratory disease, therefore, evaulation of venouse blood gases in the diagnosis of respiratory disease was found to more ifical.
The importance of arterial and venouse blood gas in the diagnosis of experimentally induced respiratory tract diseases in lambs and to the most reliable which parameters in the diagnosis of disaese were aimed to determine in this study. The lambs divided to control ( 6 lambs) and experimental ( 7 lambs) groups. Pasteurella haemolytica (8x108 CFU/ mi), Clebsiella pneumoniae (8x108 CFU/ml) and Paraenfluenza 3 viruse were inoculated by intratracheal for induced respiratory tract diseases in the lambs (experimental groups). Blood samples were taken from the femoral arteria and the jugular vein once in the control group of lambs. Blood samples were taken from the femoral arteria and the jugular vein on days 1th, 2th, 3th, and 4th of the infection in the experimental group of lambs. The WBC (p<0.001), body temperature (p<0.001), respiratory rate (p<0.001), and heart rate (p<0.01) were significantly increased in the experimental group of lambs compared with the control group of lambs pH (p<0.01). pCO2 (p<0.01), p02 (p<0.05), and oxygen saturation (p<0.05) in venouse blood were significantly different in the the experimental group of lambs compared with the control group of lambs. pCO2 (p<0.01) in arterial blood was significantly different in the the experimental group of lambs compared with the control group of lambs. In the histopathologic examination, interstitial pneumonia and pneumonia with abcessation was determined in the lung of experimental group of the lambs. The results of this study showed that, artenal blood gases did not influenced in acute respiratory enfection, but venouse blood gases did more influenced in acute res piratory disease, therefore, evaulation of venouse blood gases in the diagnosis of respiratory disease was found to more ifical.
Açıklama
Anahtar Kelimeler
Solunum yolu hastalığı, arteriyal ve venöz kan gazları, kuzu, Respiratory tract disease, arterial and venouse blood gases, lamb
Kaynak
Eurasian Journal of Veterinary Sciences
WoS Q Değeri
Scopus Q Değeri
Cilt
21
Sayı
3-4
Künye
Ok, M., Güzelbekteş, H., Şen, İ., Coşkun, A., (2005). Kuzularda Deneysel Oluşturulan Akut Solunum Si̇stemi̇ Enfeksi̇yonlarının Teşhi̇si̇nde Arteri̇yal Kan Gazlarının Önemi̇. Eurasian Journal of Veterinary Sciences, 21(3-4), 119-125.
