The Comparison of Postoperative Analgesic Effects of Preemptive Ketamine and Fentanyl Use in Mastectomy Operations

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dc.contributor.authorÖğün, C. Ö.
dc.contributor.authorDuman, A.
dc.contributor.authorÖkeşli, S.
dc.date.accessioned2020-03-26T16:37:37Z
dc.date.available2020-03-26T16:37:37Z
dc.date.issued2001
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe aim of this study was to compare the efficacy of preemptive analgesia with fentanyl or ketamine in women undergoing mastectomy for breast cancer. ASA I-II, 47 women scheduled for mastectomy were included in the study. For all patients, anesthesia was induced with thiopentale, vecuronium and maintained with O 2:N 2O (30:70) + isoflurane. Heart rate (HR), mean arterial pressure (MAP), peripheral O 2 saturation (SpO 2) were monitored. After the induction of anesthesia, the patients were randomly divided in three groups: Group K (n=16) received 1 mg/kg ketamine, while group F (n=16) received 1 ?g/kg fentanyl before the skin incisions and after excision of the specimens. Group P received isotonic saline at sametimes. No other analgesic drugs were used intraoperatively. HR, MAP, extubation times, emergency times, respiration rate, SpO 2, side effects were recorded and postoperative pain was evaluated by visual analogue scale (VAS; 0-10) and verbal rating scale (VRS) in the recovery room at full emergence (0), 1st, 2nd, 4th, 12th and 24th hours. Postoperative analgesic requirements (meperidine) were recorded. The comments of anaesthesiologist and patients about postoperative period were also evaluated. There were no differences in weight, age, emergence times, extubation times. Hemodynamic and respiratory parameters, VAS and VRS scores and meperidine requirements were similar at all times between the group K and F. The increase of postoperative nausea and vomiting in group F was significantly higher than group P but was similar between group K and P and group K and F (p<0.05). As a conclusion, both ketamine and fentanyl have premptive effects in patients undergoing mastectomy but we think that analgesic effects are probably due to administirating ketamine and fentanyl both before surgical incision and before wound closure.en_US
dc.identifier.citationÖğün, C. Ö., Duman, A., Ökeşli, S., (2001). The Comparison of Postoperative Analgesic Effects of Preemptive Ketamine and Fentanyl Use in Mastectomy Operations. Ağrı, (13), 31-40.
dc.identifier.endpage40en_US
dc.identifier.issn1300-0012en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage31en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/17662
dc.identifier.volume13en_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorÖğün, C. Ö.
dc.institutionauthorDuman, A.
dc.institutionauthorÖkeşli, S.
dc.language.isotren_US
dc.relation.ispartofAğrıen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectFentanylen_US
dc.subjectKetamineen_US
dc.subjectMastectomyen_US
dc.subjectPreemptiveen_US
dc.titleThe Comparison of Postoperative Analgesic Effects of Preemptive Ketamine and Fentanyl Use in Mastectomy Operationsen_US
dc.title.alternativeMastektomi Operasyonlarında Preemptif Uygulanan Ketamin ve Fentanilin Postoperatif Analjezik Etkinliklerinin Karşılaştırılmasıen_US
dc.typeArticleen_US

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