Evaluation of hemostatic changes during isoflurane and desflurane anaesthesia using thrombelastography in intracranial mass surgery [İntrakraniyal kitle cerrahisinde desfluran ve i?zofluran anestezisinin hemostatik sistem üzerine olan etkilerinin tromboelastografi yöntemi ile de?erlendirilmesi]
Küçük Resim Yok
Tarih
2008
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Aim: The aim of this study is evaluation of hemostatic changes during isoflurane and desflurane anaesthesia using thrombclastography in intracranial mass surgery. Material and Methods: Fourty ASA I-III patients between ages 18-65 undergoing supratentorial craniotomy operations were included in the study. Heart rate, mean arterial pressure, peripheral oxygen saturation, PaCO 2, ETCO2 pressure, peripheral body temperatures were monitorized. All patients were applied 1 pg kg-1 remifentanil iv bolus for 60 seconds during anaesthesia induction. Following the remifentanil application, 2 mg kg-1 iv bolus propofol was applied. After loss of consciousness, tracheal intubation was faeiliated with 0.5 mg kg-1 atracurium. For maintenance of anaesthesia, 0.5 MAC isoflurane for group I, 0.5 MAC desflurane for group D was used. TEG parameters were performed preoperatively, at the 60th minute of induction, and at 24th hour postoperatively. Results: No statistically significant difference was present in measurement of reaction time, coagulation time, alpha angle and maximum amplitude values among and in between the groups (P>0,05). Conclusion: In this study we compared hemostatic changes during isoflurane and desflurane anaesthesia using thrombclastography in intracranial mass surgery; we concluded that both desflurane and isoflurane do not change TEG parameters, do not have any negative effect on hemostatic system and can be used safely in major surgery such as intracranial mass surgery.
Açıklama
Anahtar Kelimeler
Desflurane, Inhalation anesthetics, Isoflurane, Supratentorial tumors, Thrombelastography
Kaynak
Revista Espanola de Cirugia Ortopedica y Traumatologia
WoS Q Değeri
Scopus Q Değeri
Q3
Cilt
52
Sayı
1
