DOES PRIMARY TUMOR RESECTION AFFECT SURVIVAL IN ELDERLY PATIENTS WITH METASTATIC GASTRIC CANCER? ABSTRACT
Küçük Resim Yok
Tarih
2016
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
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Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Giriş: Bu araştırmada 65 yaş üstü metastatik gastrik kanserli (mGK) hastalarda tanıda primer tümör rezeksiyonunun (PTR) sağ kalıma etkisinin araştırılması amaçlanmıştır. Gereç ve Yöntem: Altmış beş yaş üstü mGK'lı 98 hasta verisi Akdeniz Üniversitesi, Necmettin Erbakan Üniversitesi ve Antalya Eğitim ve Araştırma Hastanesi veritabanlarından retrospektif olarak incelendi. Hastalar PTR'ye göre PTR () ve PTR (-) olarak iki gruba ayrıldı. Bulgular: PTR () grupta medyan progresyonsuz sağkalım 10.2 [95% CI 6.6-13.7] ay iken, PTR (-) grupta 5.9 [95% CI 2.6-9.3] aydı (p0.054). Genel sağkalım açısından incelendiğinde PTR () grubun sağkalım süresi anlamlı olarak daha yüksek bulundu (p0.001). PTR () grubun sağkalımı 11.5 [95% CI 8.4-14.6] ay iken, PTR (-) grubun sağkalımı 7.2 [95% CI 4.3-10.0] aydı. Çok değişkenli analizde hiç bir parametre bağımsız prognostik faktör olarak bulunamadı. Sonuç: Altmış beş yaş üstü tanıda MGC hastalarda primer tümörün cerrahisinin sağ kalıma faydası olabilir.
Introduction: In this study, the effect of primary tumor resection (PTR) on the survival ofpatients with metastatic gastric carcinoma (mCG) aged over 65 years was aimed to be searched. Materials and Method: In total, 98 patients with mCG from the Akdeniz University,Necmettin Erbakan University, and Antalya Training and Research Hospital databases who wereaged over 65 years were retrospectively evaluated. The patients were divided into two groupsbased on PTR: PTR () and PTR (-).Results: The median progression-free survival in the PTR () group was 10.2 months (95%confidence interval [CI] 6.6-13.7) and in the PTR (-) group was 5.9 months (95% CI 2.6-9.3)(p0.054). When we evaluated the overall survival (OS) of the groups, the median OS was significantly higher in the PTR () group (11.5 months, 95% CI 8.4-14.6) than in the PTR (-) group(7.2 months, 95% CI 4.3-10.0) (p0.001). In the final multivariate analysis, none of the parameters studied were independent prognostic factors. Conclusion: PTR may be beneficial for the survival of patients with mGC aged over 65 years.
Introduction: In this study, the effect of primary tumor resection (PTR) on the survival ofpatients with metastatic gastric carcinoma (mCG) aged over 65 years was aimed to be searched. Materials and Method: In total, 98 patients with mCG from the Akdeniz University,Necmettin Erbakan University, and Antalya Training and Research Hospital databases who wereaged over 65 years were retrospectively evaluated. The patients were divided into two groupsbased on PTR: PTR () and PTR (-).Results: The median progression-free survival in the PTR () group was 10.2 months (95%confidence interval [CI] 6.6-13.7) and in the PTR (-) group was 5.9 months (95% CI 2.6-9.3)(p0.054). When we evaluated the overall survival (OS) of the groups, the median OS was significantly higher in the PTR () group (11.5 months, 95% CI 8.4-14.6) than in the PTR (-) group(7.2 months, 95% CI 4.3-10.0) (p0.001). In the final multivariate analysis, none of the parameters studied were independent prognostic factors. Conclusion: PTR may be beneficial for the survival of patients with mGC aged over 65 years.
Açıklama
Anahtar Kelimeler
Cerrahi
Kaynak
Türk Geriatri Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
19
Sayı
3
