Development of doxorubicin loading platform based albumin-sporopollenin as drug carrier
Küçük Resim Yok
Tarih
2016
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier B.V.
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Albumin is thought as an drug carrier for doxorubicin (DOX). The binding of doxorubicin to albumin was studied on the surface of sporopolleninin (SP) to produce a new drug system based natural materials. Human serum albumin (HSA) was immobilized on SPIONs in 20 mM Tris buffer, 7.4 of pH. Data showed that binding amount of HSA has been found to be as 285.53 ?g to the 25 mg of Sporopolleninin which also bounded 319.76 ?M of DOX. Binding of protein and drug to Sp were clarified by SEM, EDX and FT-IR analysis. © 2016.
Açıklama
Anahtar Kelimeler
Doxorubicin, Fluorescence spectroscopy, Magnetic nanoparticles, Protein
Kaynak
Biochemistry and Biophysics Reports
WoS Q Değeri
Scopus Q Değeri
Q2
Cilt
7
