Evaluation of doses in the Wernicke and Broca's areas using two different technique in patients with right frontal glioblastoma multiforme
Küçük Resim Yok
Tarih
2013
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
IJRR-IRANIAN JOURNAL RADIATION RES
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Background: Broca's and Wernicke's areas, which are important language areas of brain, are commonly irradiated in patients with right frontal lobe glioblastomamultiforme (GBM). We aimed to compare two different treatment planning techniques in terms of the doses in the Broca's and Wernicke's areas for the patients with right frontal GBM. Materials and Methods: Two different treatment planning techniques of right frontal GBM were generated for Rando phantom: two field technique using parallel opposed beams and three field techniques. Both plans were compared for doses in planning target volume (PTV), Broca's and Wernicke's areas. Additionally to test the accuracy of treatment planning system (TPS) dose calculation; thermoluminescent dosimeters (TLD) were used. Results: The three field technique allowed the lower doses in the Broca's and Wernickes's areas. The doses calculated in the Broca'sand Wernicke's areas were 0.98% +/- 0.03 and 0.09% +/- 0.06 of the isocenter dose with three field and 1.06% +/- 0.04 and 0.133% +/- 0.03 of the isocenter dose with two field techniques respectively. When the doses measured by TLD and calculated with TPS were compared; the differences were 3.23% and 2.92 % for Broca's area, and 4.12 % and 3.95% for Wernicke's area for two field and three field techniques respectively. Conclusion: There was a good agreement between TPS and TLD calculations for both techniques. Three field techniques seem to be more advantageous than two field technique with respect to doses of Broca's and Wernicke's areas. However this finding should be clarified with further clinical studies.
Açıklama
Anahtar Kelimeler
Broca's area, glioblastomamultiforme, Rando phantom, Wernicke's area, thermoluminescent dosimetry
Kaynak
INTERNATIONAL JOURNAL OF RADIATION RESEARCH
WoS Q Değeri
N/A
Scopus Q Değeri
Cilt
11
Sayı
1
