Blink Reflex Alterations in Chronic Renal Failure

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dc.contributor.authorKozak, Hasan Huseyin
dc.contributor.authorDemir, Orhan
dc.contributor.authorGuney, Figen
dc.date.accessioned2020-03-26T18:24:08Z
dc.date.available2020-03-26T18:24:08Z
dc.date.issued2012
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjective: The purpose of this study was to investigate the effects of hemodialysis and peritoneal dialysis on the peripheral and central nervous system in patients with uremia associated with chronic renal failure. Method: In this study, 35 hemodialysis and 35 peritoneal dialysis patients were compared with 70 healthy controls by working in blink reflex after assessment of peripheral neuropathy by neurological examination and performing EMG. Results: Ipsilateral R2 (R2i) and contralateral R2 (R2c) response latencies were found to be significantly prolonged in patients with chronic renal failure compared to those of controls. Also, latencies of R2 responses in hemodialysis patients, in whom polyneuropathy was detected, were significantly longer than those of the peritoneal dialysis patients, while latencies of R1 responses were unaffected. Conclusion: For extraaxial lesions, R2 is less sensitive than R1, but in intraaxial lesions abnormality of R2 is as frequent as short latency responses, the R2 being more complex and spreads to the caudal medulla. Hence, in chronic renal failure patients sparing of the R1 and prolongation of the R2 indicates a subclinical intraaxial involvement. There was no significant difference in R1, R2i and R2c values between peritonal dialysis patients with polyneuropathy and controls. R1 values in hemodialysis patients with polyneuropathy were found to be within normal range while R2i and R2c values were significantly prolonged when compared to controls; suggesting that intraaxial subclinical involvement is more frequently seen in hemodialysis patients. (Archives of Neuropsychiatry 2012; 49: 102-107)en_US
dc.identifier.doi10.4274/npa.y5990en_US
dc.identifier.endpage107en_US
dc.identifier.issn1300-0667en_US
dc.identifier.issn1309-4866en_US
dc.identifier.issue2en_US
dc.identifier.startpage102en_US
dc.identifier.urihttps://dx.doi.org/10.4274/npa.y5990
dc.identifier.urihttps://hdl.handle.net/20.500.12395/27794
dc.identifier.volume49en_US
dc.identifier.wosWOS:000305733300005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isotren_US
dc.publisherAVESen_US
dc.relation.ispartofNOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectBlink reflexen_US
dc.subjectchronic renal failureen_US
dc.subjecthemodialysisen_US
dc.subjectperitoneal dialysisen_US
dc.titleBlink Reflex Alterations in Chronic Renal Failureen_US
dc.typeArticleen_US

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