Kronik İdiyopatik Ürtikerli Olgularda Tüberkülin Deri Testi Yanıtı ve T-Lenfosit Alt Grupları
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Tarih
2007
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
AMAÇ: Otolog serum testinin (OST) otoimmün ürtiker tanısında önemli bir rol oynadığı bilinmektedir. Bu çalışmada OST ve hücresel immünite belirleyicilerinin ilişkili olup olmadıklarını araştırdık. GEREÇ-YÖNTEM: Bu amaçla 68 hasta ve 37 kontrol grubuna OST ve tüberkülin deri testi (TDT) uygulandı ve T-lenfosit alt grupları ölçüldü. BULGULAR: OST kontrol grubuna göre ürtikerli hastalarda anlamlı olarak pozitif bulundu. TDT yanıtı 32 hastada pozitifti. T-lenfosit alt grupları CD4: %41.33.4, CD8: %346.5, CD4/CD8: %1.2, CD3: %668.8 şeklindeydi. SONUÇ: Sonuç olarak kronik ürtiker hastalarında OST’nin, TDT yanıtı ve T-lenfosit alt grupları ile ilişkili olmadığını belirledik.
Background and Design: It has been demonstrated that the autologous serum skin test (ASST) has an important role in clinical test for detection of autoimmune-based urticaria. The aim of this study was to evaluate the ASST and cell immunity modifiers. MATERIALS-METHODS: We examined 68 patients and 37 control subjects, performed ASST and tuberculin skin reactivity (TST) and measured T-lymphocyte subsets. RESULTS: ASST was significantly positive in urticaria patients compared to control subjects. Thirty-two patients had positive TST reactivity. T-lymphocyte subsets were as follows: CD4: %41.3±3.4, CD8: %34±6.5, CD4/CD8: %1.2, CD3: %66±8.8. ASST was not related to the TST reactivity and T-lymphocyte subsets. CONCLUSION: These data provided that ASST does not seem to be associated with TST reactivity and T-lymphocyte subsets.
Background and Design: It has been demonstrated that the autologous serum skin test (ASST) has an important role in clinical test for detection of autoimmune-based urticaria. The aim of this study was to evaluate the ASST and cell immunity modifiers. MATERIALS-METHODS: We examined 68 patients and 37 control subjects, performed ASST and tuberculin skin reactivity (TST) and measured T-lymphocyte subsets. RESULTS: ASST was significantly positive in urticaria patients compared to control subjects. Thirty-two patients had positive TST reactivity. T-lymphocyte subsets were as follows: CD4: %41.3±3.4, CD8: %34±6.5, CD4/CD8: %1.2, CD3: %66±8.8. ASST was not related to the TST reactivity and T-lymphocyte subsets. CONCLUSION: These data provided that ASST does not seem to be associated with TST reactivity and T-lymphocyte subsets.
Açıklama
Anahtar Kelimeler
Dermatoloji, Kronik idiyopatik ürtiker, tüberkülin deri testi, T-lenfosit alt grupları, Chronic idiopathic urticaria, tuberculin skin test, T-lymphocyte subgroups
Kaynak
Türkderm-Deri Hastalıkları ve Frengi Arşivi
WoS Q Değeri
Scopus Q Değeri
Cilt
41
Sayı
2
Künye
Engin, B., Özdemir, M., Mevlitoğlu, İ., (2007). Kronik İdiyopatik Ürtikerli Olgularda Tüberkülin Deri Testi Yanıtı ve T-Lenfosit Alt Grupları. Türkderm-Deri Hastalıkları ve Frengi Arşivi, 41(2), 54-56.
