İlaç kötü kullanımı başağrısı
Küçük Resim Yok
Tarih
1999
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Migren ve gerilim başağrılarının tedavileri sırasında analjezik, antienflamatuar, ergotamin, sedatif ve hipnotiklerin belirli dozların üzerinde kullanılması, primer başağrısının seyrini değiştirmekte, kronik günlük başağrısı ortaya çıkmaktadır. Buna "ilaç kötü kullanımı başağrısı" (İKKB) denir. Bu çalışmada Selçuk Üniversitesi Tıp Fakültesi Nöroloji Anabilim Dalı Polikliniği'ne başvuran 360 başağrısı hastasının 18'i Uluslararası Başağrısı Derneği (İHS) kriterlerine göre İKKB olarak belirlenmiştir (%5). 10 hastanın primer başağrısı migren, 8 hastanın ise gerilim başağrısıdır. 5 hastada ilaç yan etkisi (ergotizm) gözlenmiştir. Kötü kullanımı en sık görülen ilaçlar parasetamol (%50), metamizol (%38.8) ve ergotamin (%27.7)'dir. 12 hastada ilk 10 gün içinde, 5 hastada ilk 1 ay içinde, 1 hastada da 2 ay içinde ağrı şiddetinde azalma olmuş, 2 aylık takipte, 3 hastada (%11.7) relaps gözlenmiştir. Eğitim düzeyi düştükçe ilaç kötü kullanım oranının arttığı görülmüştür. Kronik, günlük başağrısı olan, ilaç tedavisine cevap vermeyen hastalarda İKKB akla gelmeli, günlük-aylık ortalama ilaç miktarları ve kullanım süreleri dikkatle sorgulanmalıdır.
Excessive and frequent use of antiinflammatories, sedatives, hypnotics and ergotamine in the treatment of primary headache conditions such as tension-type headache and migraine may transform the characteristics of the primary headache in to the chronic daily headache so called "drug abuse headache". In this study 18 of 360 headache patients admitted to the outpatient clinic of Neurology Department of Selçuk University School of Medicine were diagnosed as drug abuse headache using the diagnostic criteria of the IHS. The primary headache condition was diagnosed as migraine in 10 patient and tension-type headache in 8. Ergotism was observed in 5 patients. The most frequently abused drugs were paracetamol (%50), metamizol (%38.8) and ergotamine (%27.7). In 12 patients improvement was observed in the first ten days and in 5 patients in the first month, in 1 patient in the second month. 3 patients (11.7) showed relaps in 2 months follow-up period. An inverse relationship was observed between educational level and percentage of drug abused patients. The diagnosis of drug abuse headache should be considered in chronic daily headache patients unresponsive to treatment and these patients should be carefully questioned about daily and monthly amount and usage period of the drugs.
Excessive and frequent use of antiinflammatories, sedatives, hypnotics and ergotamine in the treatment of primary headache conditions such as tension-type headache and migraine may transform the characteristics of the primary headache in to the chronic daily headache so called "drug abuse headache". In this study 18 of 360 headache patients admitted to the outpatient clinic of Neurology Department of Selçuk University School of Medicine were diagnosed as drug abuse headache using the diagnostic criteria of the IHS. The primary headache condition was diagnosed as migraine in 10 patient and tension-type headache in 8. Ergotism was observed in 5 patients. The most frequently abused drugs were paracetamol (%50), metamizol (%38.8) and ergotamine (%27.7). In 12 patients improvement was observed in the first ten days and in 5 patients in the first month, in 1 patient in the second month. 3 patients (11.7) showed relaps in 2 months follow-up period. An inverse relationship was observed between educational level and percentage of drug abused patients. The diagnosis of drug abuse headache should be considered in chronic daily headache patients unresponsive to treatment and these patients should be carefully questioned about daily and monthly amount and usage period of the drugs.
Açıklama
Anahtar Kelimeler
Nörolojik Bilimler
Kaynak
Türk Beyin Damar Hastalıkları Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
5
Sayı
1
