Determination of antiviral activity and cytotoxicity of selected sage (Salvia L.) species

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dc.contributor.authorÖzçelik B.
dc.contributor.authorErdo?an Orhan I.
dc.contributor.authorKan Y.
dc.date.accessioned2020-03-26T18:22:12Z
dc.date.available2020-03-26T18:22:12Z
dc.date.issued2011
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe objective of this study was to examine antiviral property and cytotoxicity of the extracts prepared from the selected Salvia species (Lamiaceae) growing in Turkey. The chloroform and methanol extracts from 14 Salvia species (S. albimaculata, S. aucheri var. canescens, S. candidissima subsp. occidentalis, S. ceratophylla, S. cryptantha, S. cyanescens, S. frigida, S. forskahlei, S. halophila, S. migrostegia, S. multicaulis, S. sclarea, S. syriaca, and S. verticillata subsp. amasiaca) were tested against Herpes simplex (type-1, HSV-1) and Parainfluenza (type-3, PI-3) using Madin-Darby Bovine Kidney and Vero cell lines. Cytotoxicity of the extracts was determined as maximum non-toxic concentrations (MNTCs). The chloroform extracts of S. cyanescens and S. microstegia were found to inhibit both HSV-1 and PI-3 effectively. Therefore, these species could proceed to further evaluation for their possible antiviral components.en_US
dc.identifier.endpage160en_US
dc.identifier.issn1300-4182en_US
dc.identifier.issue3en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage155en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/27211
dc.identifier.volume36en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.relation.ispartofFabad Journal of Pharmaceutical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectAntiviral activityen_US
dc.subjectCytotoxicityen_US
dc.subjectLamiaceaeen_US
dc.subjectSalviaen_US
dc.titleDetermination of antiviral activity and cytotoxicity of selected sage (Salvia L.) speciesen_US
dc.typeArticleen_US

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