A comparison of maternal and fetal outcomes of pregnancies complicated by moderate to severe thrombocytopenia caused by gestational thrombocytopenia preeclampsia / hellp syndrome and immune thrombocytopenic purpura
Küçük Resim Yok
Tarih
2008
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Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Bu çalışmada gestasyonel trombositopeni (GT), preeklamp-si/HELLP sendromu ve immün trombositopenik purpuranm neden olduğu orta ve şiddetli trombositopenilerde obstetrik risk faktörlerini, komplikasyonlarını ve gebelik sonuçlarının karşılaştırılması amaçlandı. Çalışmaya trombosit sayısı 100.000/mm3'den düşük olan 135 kadın alındı. Tanılar Hematoloji laboratuvarı tarafından konuldu. Olguların ve yeni doğanların hastane seyirlerindeki klinik özellikleri kaydedildi. Şiddetli trombositopeni GT grubunda diğer iki gruba göre daha düşük gözlendi. Preeklampsi/HELLP sendromlularda oligo-hidramnios, intrauterin gelişme geriliği ve ablatio plasenta yüksek oranlarda saptandı. Bir ve 5. dakikada Apgar skor oranları (7), pH değerleri (7,2) ve mekonyumlu amniyotik sıvı oranları preeklampsi/HELLP sendromlularda daha yüksekti. Neonatal trombositopeni 5 yeni doğanda tespit edildi. Sonuç olarak preeklampsi/HELLP sendromunun eşlik ettiği trombositopenili olgular, obstetrik ve fetal sonuçlar açısından en olumsuz grup olarak saptandı.
OBJECTIVE: Aim of this study was to compare obstetric risk factors and complications, and outcomes of pregnancies associated with moderate to severe thrombocytopenia caused by gestational thrombocytopenia (GT), preeclampsia/HELLP syndrome, and immune thrombocytopenic purpura (ITP). STUDY DESIGN: The study was composed of 135 women with a platelet count below 100.000/mm3. The characteristics and clinical details of all women and neonatal were recorded during their hospital course. RESULTS: The ratio of severe thrombocytopenia was observed significantly lower in GT group compared with preeclampsia / HELLP syndrome and ITP groups. Higher rates of oligohydroamnios, IUGR, and placental abruption were found among patients in preeclampsiaHELLP syndrome group. The rates of Apgar scores (<7) at 1 and 5 min, pH values (<7,2), and amniotic fluid with meconium were higher in preeclampsia / HELLP syndrome group. Neonatal thrombocytopenia was recorded in a total of 5 infants. CONCLUSION: The thrombocytopenia with preeclampsia/HELLP syndrome had less favorable obstetric and fetal outcomes.
OBJECTIVE: Aim of this study was to compare obstetric risk factors and complications, and outcomes of pregnancies associated with moderate to severe thrombocytopenia caused by gestational thrombocytopenia (GT), preeclampsia/HELLP syndrome, and immune thrombocytopenic purpura (ITP). STUDY DESIGN: The study was composed of 135 women with a platelet count below 100.000/mm3. The characteristics and clinical details of all women and neonatal were recorded during their hospital course. RESULTS: The ratio of severe thrombocytopenia was observed significantly lower in GT group compared with preeclampsia / HELLP syndrome and ITP groups. Higher rates of oligohydroamnios, IUGR, and placental abruption were found among patients in preeclampsiaHELLP syndrome group. The rates of Apgar scores (<7) at 1 and 5 min, pH values (<7,2), and amniotic fluid with meconium were higher in preeclampsia / HELLP syndrome group. Neonatal thrombocytopenia was recorded in a total of 5 infants. CONCLUSION: The thrombocytopenia with preeclampsia/HELLP syndrome had less favorable obstetric and fetal outcomes.
Açıklama
Anahtar Kelimeler
Kadın Hastalıkları ve Doğum
Kaynak
GORM:Gynecology Obstetrics & Reproductive Medicine
WoS Q Değeri
Scopus Q Değeri
Cilt
14
Sayı
3
