Enzyme-free colorimetric sensing of glucose using L-cysteine functionalized silver nanoparticles

dc.contributor.authorAdnan, Sumaira
dc.contributor.authorKalwar, Nazar Hussain
dc.contributor.authorAbbas, Malik Waseem
dc.contributor.authorSoomro, Razium Ali
dc.contributor.authorSaand, Mumtaz Ali
dc.contributor.authorAwan, Fazli Rabbi
dc.contributor.authorAvcı, Ahmet
dc.contributor.authorPehlivan, Erol
dc.contributor.authorBajwa, Sadia
dc.date.accessioned2020-03-26T20:13:56Z
dc.date.available2020-03-26T20:13:56Z
dc.date.issued2019
dc.departmentSelçuk Üniversitesi, Mühendislik Fakültesi, Makine Mühendisliği Bölümüen_US
dc.description.abstractThe study demonstrates an efficient, simple and on-site viable approach for sensitive determination of blood glucose using colorimetric sensing approach. The devised colorimetric sensor works based on cysteine functionalized silver nanoparticles. The as-synthesized Ag NPs were elaborately characterized using advanced analytical techniques such as ultra-violet visible spectroscopy, Fourier transform infrared spectroscopy, transmission electron microscopy, atomic force microscopy and X-ray diffraction. The detection of glucose was carried under ambient air conditions where change in the optical characteristics of Ag NPs and subsequent interaction between glucose and functional moiety (i.e. surface bind cysteine) of Ag NPs was considered as the signal response. This interaction led to direct detection of glucose in the concentration range between 0.01 to 0.17 mu M with limit of detection up to 1 x 10(-4) mu M. It is worthwhile mentioning that success of the assay lies in application of the developed colorimetric sensor in real blood glucose measurements, which also proved its capability for field based analysis. In addition its simple design, low cost, and more reliability signifies the usefulness of colorimetric sensor and it can be extended monitor other biologically important molecules.en_US
dc.description.sponsorshipScientific and Technological Research Council of Turkey (TUBITAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [1059B211600383]en_US
dc.description.sponsorshipThis study was funded by The Scientific and Technological Research Council of Turkey (TUBITAK) under 2221-Fellowships for Visiting Scientists and Scientists on Sabbatical Leave, the Grant Number of the project is 1059B211600383.en_US
dc.identifier.citationAdnan, S., Kalwar, N. H., Abbas, M. W., Soomro, R. A., Saand, M. A., Awan, F. R., Avci, A., Pehlivan, E., Bajwa, S. (2019). Enzyme-Free Colorimetric Sensing of Glucose Using L-Cysteine Functionalized Silver Nanoparticles. SN Applied Sciences, 1(2), 144.
dc.identifier.doi10.1007/s42452-018-0117-5en_US
dc.identifier.issn2523-3963en_US
dc.identifier.issn2523-3971en_US
dc.identifier.issue2en_US
dc.identifier.pmid#YOKen_US
dc.identifier.urihttps://dx.doi.org/10.1007/s42452-018-0117-5
dc.identifier.urihttps://hdl.handle.net/20.500.12395/37791
dc.identifier.volume1en_US
dc.identifier.wosWOS:000473543500005en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.institutionauthorKalwar, Nazar Hussain
dc.institutionauthorAvcı, Ahmet
dc.institutionauthorPehlivan, Erol
dc.language.isoenen_US
dc.publisherSPRINGER INTERNATIONAL PUBLISHING AGen_US
dc.relation.ispartofSN APPLIED SCIENCESen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectGlucoseen_US
dc.subjectEnzyme freeen_US
dc.subjectColorimetric probesen_US
dc.subjectFunctionalized Ag NPsen_US
dc.titleEnzyme-free colorimetric sensing of glucose using L-cysteine functionalized silver nanoparticlesen_US
dc.typeArticleen_US

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