Normal Koroner Arterlere Sahip Sol Dal Bloklu Hastalarda Egzersiz Ti-201 Spect ve Tc-99m Tetrofosmin Spect Sonuçlarının Karşılaştırılması
Küçük Resim Yok
Tarih
2001
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Sol dal bloklu hastalarda (LBBB), sol ön inen koroner arter (LAD) sahasında sintigrafık çalışmalarda sıklıkla yalancı pozitif perfüzyon defektleri vardır. Yüksek orandaki yalancı pozitif sonuçlar nedeni ile sintigrafık çalışmaların koroner arter hastalığı tanısı koymadaki değeri kısıtlıdır. Bu çalışmada koroner anjiyografik olarak normal koroner arterlere sahip hastalarda, egzersiz ile yapılan Thallium - 201 single photon emission komputerize tomografi (Tl-201 SPECT) ve Teknesyum 99 m- Tetrofosmin (Tc-99m Tetrofosmin) SPECT sonuçlarını karşılaştırmayı amaçladık. Çalışmaya koroner anjiyograflk olarak normal koroner arterler tespit edilen 66 LBBB 'lı hasta dahil edildi. Tüm hastalara egzersiz ile Tl-201 SPECT ve Tc-99m Tetrofosmin SPECT uygulandı. Tl-201 SPECT ile 33 (%50) hastada yalancı pozitif sonuç elde edilirken, Tc-99m Tetrofosmin ile 31 hastada %47 yalancı pozitif sonuç elde edildi (p0.05). Egzersiz Tl-201 SPECT ve Tc-99m Tetrofosmin SPECT sonuçları birebir karşılaştırıldığında aradaki uyum %97 olarak bulundu. Sonuç olarak normal koroner arterlere sahip LBBB'U hastalarda Tl-201 ve Tc-99m Tetrofosmin SPECT sonuçları arasındaki yalancı pozitif sonuçlar yönünden istatistiksel anlamlı fark yoktur. Bu nedenle LBBB 'de fonksiyonel iskemiye bağlı olduğu düşünülen yalancı pozitif sonuçlan azaltmak amacı ile yeni sintigrafık ajan veya yöntemlerin bulunmasına gerek vardır.
Patients with left bundle branch block (LBBB) often have false positive perfusion defects during scintigraphic studies in myocardial wall supplied by left anterior descending (LAD coronary artery. Diagnostic value of scintigraphic studies in patients with LBBB is limited due to high rate of false positive perfusion defects. We aimed to assess and compare the results of exercise Tl-201 Single Photon Emission Computerized Tomography (SPECT) and Tc-99m tetrofosmin SPECT in patients with LBBB and normal coronary arteries. Sixty six patients with LBBB and normal coronary artery proven angiographycally were included in the study. All patients were studied with exercise Tl-201 SPECT and Tc-99m SPECT. in Tl-201 SPECT study, 33 patients (50) had false positive defects in LAD coronary artery area and 31 patients (47%) had also alse positive defects in LAD coronary artery area in Tc-99m SPECT study. The agreement between Tl-201 SPECT and Tc-99m SPECT was found as 97%. in conclusion in patients patients with LBBB there is no statistical signifıcant difference between Tl-201 SPECT and Tc-99m SPECT in respect to false positive perfusion defects. So some new scintigraphic agents and method are needed to be found for lessening the false positive perfusion defects which is thought to be due to functional ischemia in patients with LBBB and normal coronary artery. Key Words: Left bundle branch block, Normal coronary artery, Myocard perfusion scintigraphy.
Patients with left bundle branch block (LBBB) often have false positive perfusion defects during scintigraphic studies in myocardial wall supplied by left anterior descending (LAD coronary artery. Diagnostic value of scintigraphic studies in patients with LBBB is limited due to high rate of false positive perfusion defects. We aimed to assess and compare the results of exercise Tl-201 Single Photon Emission Computerized Tomography (SPECT) and Tc-99m tetrofosmin SPECT in patients with LBBB and normal coronary arteries. Sixty six patients with LBBB and normal coronary artery proven angiographycally were included in the study. All patients were studied with exercise Tl-201 SPECT and Tc-99m SPECT. in Tl-201 SPECT study, 33 patients (50) had false positive defects in LAD coronary artery area and 31 patients (47%) had also alse positive defects in LAD coronary artery area in Tc-99m SPECT study. The agreement between Tl-201 SPECT and Tc-99m SPECT was found as 97%. in conclusion in patients patients with LBBB there is no statistical signifıcant difference between Tl-201 SPECT and Tc-99m SPECT in respect to false positive perfusion defects. So some new scintigraphic agents and method are needed to be found for lessening the false positive perfusion defects which is thought to be due to functional ischemia in patients with LBBB and normal coronary artery. Key Words: Left bundle branch block, Normal coronary artery, Myocard perfusion scintigraphy.
Açıklama
Anahtar Kelimeler
Kalp ve Kalp Damar Sistemi
Kaynak
MN Kardiyoloji
WoS Q Değeri
Scopus Q Değeri
Cilt
8
Sayı
6
Künye
Temizhan, A., Tandoğan, İ., Yetkin, E., Naldöken, S., Çamsarı, A., Dereağzı, F., Şaşmaz, A., (2000). Normal Koroner Arterlere Sahip Sol Dal Bloklu Hastalarda Egzersiz Ti-201 Spect ve Tc-99m Tetrofosmin Spect Sonuçlarının Karşılaştırılması. MN Kardiyoloji, 8(6), 410-414.
