Bacteremia Following Exchange Transfusion in Infants
Küçük Resim Yok
Tarih
2003
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The hypothesis is that transient bacteremia following exchange transfusion in infants may occur; however, it is not associated with clinical evidence of disease. Therefore, the objective of this study is to evaluate the significance of this bacteremia in terms of clinical evidence of infection. We studied 155 patients with jaundice requiring an immediate exchange transfusion (ET). Blood cultures were taken before, soon after completion of the procedure and at 24h later respectively. The clinical course of each patient after the procedure was monitored in terms of evidence of sepsis for minimum of five days. One hundred twenty of the 155 patients underwent a single ET whereas 35 patients required a second ET within 8 to 12 hours. Blood cultures obtained before ET (preexchange specimen) and at 24h later were sterile in all patients. Eighteen (11.6%) patients had positive blood cultures soon after completion of the procedure. Eleven of 120 (9.1%) patients with a single ET had positive blood cultures. Seven of 35 (20%) patients with the second ETs had positive blood cultures. There was a significant statistical difference in terms of bacteremia between the group of single ET and the group of second ETs. (p<0.001). The incidence of requirement for clinical infection was 1 out of 18 (5.5%) infants who developed bacteremia. Bacteremia resolved spontaneously in the majority of infants. However 1 in 18 (5.5%) of the bacteremic infants did develop symptoms and required treatment.
Açıklama
Anahtar Kelimeler
Bacteremia, Exchange transfusion, Umbilical vein catheterization
Kaynak
International Pediatrics
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
18
Sayı
3
