The Effects of Halothane and Sevoflurane on Qtc Interval

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dc.contributor.authorReisli, Ruhiye
dc.contributor.authorÇelik, J.
dc.contributor.authorÖzdemir, K.
dc.contributor.authorTavlan, A.
dc.contributor.authorApillioğlu, S.
dc.contributor.authorÖkeşli, S.
dc.date.accessioned2020-03-26T16:36:25Z
dc.date.available2020-03-26T16:36:25Z
dc.date.issued2000
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractProlongation of the QT interval may cause hazardous arrhythmias. The effects of halothane and sevoflurane on the Q T interval (QTc) have been investigated during induction of anaesthesia in 30 ASA I-II class patients. No premedication was used to avoid the effects of other anaesthetic agents. Anaesthesia was induced with either halothane (n=15) or sevoflurane (n=15), and inspired concentration was increased gradually to achieve a constant initial end-tidal concentration of 2 MAC. After pupils came to midline 0.05 mg/kg atracurium was administered and end-tidal concentration was reduced to 1 MAC. Recordings of ECG, heart rate, systolic and diastolic arterial blood pressure were obtained at the following times: prior to induction of anaesthesia, after the lost of eye slash reflex, 3 min following atracurium administration, 1 and 3 min after tracheal intubation. QT interval was corrected for the heart rate (QTc). Both halothane and sevoflurane prolonged QTc one minute after the tracheal intubation, but it was statistically significant only in sevoflurane group (p<0.05). The heart rate increased 1 and 3 rain after tracheal intubation with sevoflurane (p<0.05). In both groups, systolic and diastolic arterial blood pressures decreased after induction of anaesthesia (p<0.05). In conclusion the prolongation of the QTc interval by halothane and sevoflurane suggests that caution should be used during administration of these agents to patients with long QTc syndrome.en_US
dc.identifier.citationReisli, R., Çelik, J., Özdemir, K., Tavlan, A., Apillioğlu, S., Ökeşli, S., (2000). The Effects of Halothane and Sevoflurane on Qtc Interval. Türk Anesteziyoloji ve Reanimasyon, 28(10), 500-504.
dc.identifier.endpage504en_US
dc.identifier.issn1016-5150en_US
dc.identifier.issue10en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage500en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/17293
dc.identifier.volume28en_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorReisli, Ruhiye
dc.institutionauthorÇelik, J.
dc.institutionauthorÖzdemir, K.
dc.institutionauthorTavlan, A.
dc.institutionauthorApillioğlu, S.
dc.institutionauthorÖkeşli, S.
dc.language.isotren_US
dc.relation.ispartofTürk Anesteziyoloji ve Reanimasyonen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectHalothaneen_US
dc.subjectQT intervalen_US
dc.subjectSevofluraneen_US
dc.titleThe Effects of Halothane and Sevoflurane on Qtc Intervalen_US
dc.title.alternativeHalotan ve Sevofluran'in Qt Intervaline Etkisien_US
dc.typeArticleen_US

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