The clues of the primary immunodeficiency in newborn [Yenido?an bebekte immün yetersizli?in ipuçlari]

The specific antibodies were low in sera of the neonates with no immunological memory and low ability to develop specifik antibody. Defense against infection in neonate is predominantly dependent on innate immunity. Because the functional capacity of the other compartments of the immune system is insufficient, the newborns have a higher frequency of infections than older children and adults. It is an important issue to know the some clues such as a family history of immunodeficiency, late separation of umblical cord, lymphopenia, moniliasis, absence of peripheral lymphoid tissue, organ abscesses and hypocalsemic tetani that indicate immunodeficiency in a newborn with insufficient immune system. It is possible to determine this clues with an adequate history, well-done physical examination and a careful clinical follow up.