Sigaranın Koroner Arter Hastalığının Anjiyografik Özelliklerine Etkisi ve Diğer Risk Faktörleriyle Olan İlişkisi
Küçük Resim Yok
Tarih
2001
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Sigara içen miyokard infarktüslü hastalarda prognozun daha iyi olması, sigara içenlerde eşlik eden risk faktörlerinin daha az olmasına ve koroner arter lezyonlarının daha az olmasına bağlanmıştır. Biz anjiografik olarak tespit edilen koroner arter lezyonlarına sigaranın etkisini ve bunun diğer risk faktörleriyle olan ilişkisini araştırmayı amaçladık. GEREÇ VE YÖNTEM: Koroner arterlerinde %50 darlık saptanan 259'u erkek 110'nu kadın 369 hasta çalışmaya dahil edildi. Hastalar sigara alışkanlıklarına göre gruplandırıldı Koroner arterlerdeki lezyonların yerleşimi, kollateral dolaşımı ve hastalık skorları belirlendi. BULGULAR: Sigara içenler daha gençti ve hipertansiyon daha az oranda tespit edildi (p0.001). İnferior Mİ geçirme sıklığı sigara içenlerde daha fazlaydı (p0.05). Koroner arter hastalık skoru ve kollateral dolaşım skoru sigara içen ve içmeyen hastalar arasında anlamlı bir fark göstermiyordu Multivariate analizlerde sigaranın lezyon yerleşimine ve hastalıklı damar sayısına anlamlı bir etkisi bulunmadı. Sigara içmeyenlerde iş ve hiperkolesterolemi (sırasıyla R0,ll, Exp B 1,05, p0,03 ve R0,13, Exp B2,42, p0,01) sigara içenlerde ise sadece diyabet koroner arter skorunu arttıran bağımsız değişkenler olarak saptandı (R0,12, Exp B2,39, p0,02). SONUÇ: Koroner arter hastalığı için risk faktörü olan sigaranın hastalığın anjiyograflk özelliklerine olan etkisi diğer risk faktörlerininki kadar belirgin değildir ve be etkisi farklı mekanizmalarla gelişmektedir.
The improved prognosis of smokers with myocardial infarction was attributed to their favorable accompanied risk factors and coronary artery lesions. We aimed to observe the effect of smoking in angiographically diagnosed coronary artery lesions and also the relationship between 'cigarette and other risk factors MATERIAL AND METHODS: Two hundered fifty-nine male and IlOfemale patients who had coronary artery lesions (>50 %) were taken to this study. Patients were grouped according to smoking status. The localization of coronary artery lesions, collateral circulations and angiographic of disease were examined. RESULTS: Smokers were younger (p<0.001) and were less frequently hypertensive (p<0.001) and more frequently" previous İnferior infarction than non-smokers (p<0.05). The scores of collateral circulation and extent of disease in smokers and non-smokers were not significantly different. in multivariate analysis, there were no effects of smoking on extention of disease and the number of vessel diseased. Age and hypercholesterolemia were determined as independent risk factors increased coronary artery scores, in non-smokers (R0,ll, Exp B 1,05, 0,03 and R0,13, Exp B2,42, p0,01, respectively) whereas diabetes was determined as independent risk factor in smokers (R0,12, Exp 2,39, p0,02). CONCLUSION: The effect of smoking on the angiographic features of coronary artery disease is not clear as in the other risk factors and this effect occurs with different mechanisms.
The improved prognosis of smokers with myocardial infarction was attributed to their favorable accompanied risk factors and coronary artery lesions. We aimed to observe the effect of smoking in angiographically diagnosed coronary artery lesions and also the relationship between 'cigarette and other risk factors MATERIAL AND METHODS: Two hundered fifty-nine male and IlOfemale patients who had coronary artery lesions (>50 %) were taken to this study. Patients were grouped according to smoking status. The localization of coronary artery lesions, collateral circulations and angiographic of disease were examined. RESULTS: Smokers were younger (p<0.001) and were less frequently hypertensive (p<0.001) and more frequently" previous İnferior infarction than non-smokers (p<0.05). The scores of collateral circulation and extent of disease in smokers and non-smokers were not significantly different. in multivariate analysis, there were no effects of smoking on extention of disease and the number of vessel diseased. Age and hypercholesterolemia were determined as independent risk factors increased coronary artery scores, in non-smokers (R0,ll, Exp B 1,05, 0,03 and R0,13, Exp B2,42, p0,01, respectively) whereas diabetes was determined as independent risk factor in smokers (R0,12, Exp 2,39, p0,02). CONCLUSION: The effect of smoking on the angiographic features of coronary artery disease is not clear as in the other risk factors and this effect occurs with different mechanisms.
Açıklama
Anahtar Kelimeler
Kalp ve Kalp Damar Sistemi
Kaynak
MN Kardiyoloji
WoS Q Değeri
Scopus Q Değeri
Cilt
8
Sayı
5
Künye
Temizhan, A., Telli, H. H., Altunkeser, B. B., Özdemir, K., Karabağ, T., Özdemir, A., Gök, H., (2001). Sigaranın Koroner Arter Hastalığının Anjiyografik Özelliklerine Etkisi ve Diğer Risk Faktörleriyle Olan İlişkisi. MN Kardiyoloji, 8(5), 363-369.
