RETRACTED: The prognostic value of serum troponin T in unstable angina (Retracted Article. See vol 145, pg E81, 2010)
dc.contributor.author | Cin, VG | |
dc.contributor.author | Gok, H | |
dc.contributor.author | Kaptanoglu, B | |
dc.date.accessioned | 2020-03-26T16:24:50Z | |
dc.date.available | 2020-03-26T16:24:50Z | |
dc.date.issued | 1996 | |
dc.department | Selçuk Üniversitesi | en_US |
dc.description.abstract | Background: Cardiac troponin T is a regulatory contractile protein not normally found in blood. Its detection in the circulation has been shown to be a sensitive and specific marker for; myocardial cell damage. We used a newly developed enzyme immunoassay fbr troponin T to determine whether its presence in the serum of patients with unstable angina was a prognostic indicator. Methods: We screened 72 patients with unstable angina (Class III, acute unstable angina) for serum creatine kinase activity, creatine kinase myocardial band (isoenzyme M) activity, and troponin T, every 8 h for 2 days after admission to the hospital. The outcomes of interest during the hospitalization were death and myocardial infarction. Results: Troponin T was detected in the serum of 24 of the 72 patients (34%) with acute angina at rest. Only four of these patients had elevated creatine kinase M activity. Of the 24 patients who were positive for troponin T, 12 had myocardial infarction, and 6 of these died during hospitalization. In contrast, only 2 of the 48 patients with angina at rest who were negative for troponin T had an acute myocardial infarction, and these patients died. Thus, 12 of the 14 patients with myocardial infarctions had detectable levels of troponin T; only 2 had elevated creatine kinase M activity. Conclusions: Cardiac troponin T in serum appears to be a more sensitive indicator of myocardial-cell injury than serum creatine kinase MB activity, and its detection in the circulation may be a useful prognostic indicator in patients with unstable angina. | en_US |
dc.identifier.endpage | 244 | en_US |
dc.identifier.issn | 0167-5273 | en_US |
dc.identifier.issn | 1874-1754 | en_US |
dc.identifier.issue | 3 | en_US |
dc.identifier.startpage | 237 | en_US |
dc.identifier.uri | https://hdl.handle.net/20.500.12395/16406 | |
dc.identifier.volume | 53 | en_US |
dc.identifier.wos | WOS:A1996UR06600007 | en_US |
dc.identifier.wosquality | N/A | en_US |
dc.indekslendigikaynak | Web of Science | en_US |
dc.language.iso | en | en_US |
dc.publisher | ELSEVIER IRELAND LTD | en_US |
dc.relation.ispartof | INTERNATIONAL JOURNAL OF CARDIOLOGY | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.selcuk | 20240510_oaig | en_US |
dc.subject | troponin T | en_US |
dc.subject | unstable angina | en_US |
dc.title | RETRACTED: The prognostic value of serum troponin T in unstable angina (Retracted Article. See vol 145, pg E81, 2010) | en_US |
dc.type | Article | en_US |
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