Are spontaneous peak flow rates predictors of weaning?

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dc.contributor.authorBahar, Ilhan
dc.contributor.authorBaldane, Suleyman
dc.contributor.authorElay, Gulseren
dc.contributor.authorCoskun, Ramazan
dc.contributor.authorGundogan, Kursat
dc.contributor.authorGuven, Muhammet
dc.contributor.authorSungur, Murat
dc.date.accessioned2020-03-26T19:00:56Z
dc.date.available2020-03-26T19:00:56Z
dc.date.issued2015
dc.departmentSelçuk Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractObjective: Numerous parameters have been suggested for the prediction of weaning from mechanical ventilation; however, these parameters have limited success in the prediction of weaning outcome. This study aims to assess the success of peak flow rates [spontaneous peak inspiratory flow rate (SPIF) and spontaneous peak expiratory flow rate (SPEF)] that were measured during a spontaneous breathing trial (SBT) for the prediction of weaning outcome. Material and Methods: Patients who were managed and who received mechanical ventilation support for at least 24 h in the Internal Medicine and General Surgery Intensive Care Units of Erciyes University, School of Medicine between March, 2011 and May, 2012 were included in this study. Over 30 min, SPIF and SPEF values were measured during SBT in patients who were spontaneously breathing through a T-tube. Patients who tolerated the 30-min SBT were extubated. Patients who did not require reintubation for 48 h after extubation were considered as successful weaning, whereas those who required re-intubation were considered as weaning failure. Results: The study was completed with a total of 36 patients with 11 patients in the failure group and 25 in the success group. In both the groups, the area under curve (AUC) was calculated for each minute via ROC analysis using minute SPIF and SPEF values that were measured during SBT. The maximum AUC was calculated at 23 min for SPIF (0.564; 95% CI: 0.363-0.764) and at 9 min for SPEF (0.542; 95% CI: 0.316-0.3769). When the cut-off value for SPIF was accepted as >26.7 l/min at 23 min, sensitivity and specificity were calculated as 72.0% and 48.0%, respectively. When the cut-off value for SPEF was accepted as >24.7 l/min at 9 min, sensitivity and specificity were calculated as 63.6% and 48.0%, respectively. Conclusion: We believe that minute SPIF measurement, which has better sensitivity, and minute SPEF measurement, which has better specificity, compared with the available traditional predictors may be used as potential bedside weaning predictors when evaluated in comprehensive studies.en_US
dc.identifier.citationBahar, İ., Baldane, S., Elay, G., Coşkun, R., Gündogan, K., Sungur, M. (2015). Are Spontaneous Peak Flow Rates Predictors of Weaning?. Journal of Medical and Surgical Intensive Care Medicine, 6(2), 39-43.
dc.identifier.doi10.5152/dcbybd.2015.911en_US
dc.identifier.endpage43en_US
dc.identifier.issn1309-1689en_US
dc.identifier.issn1309-6222en_US
dc.identifier.issue2en_US
dc.identifier.pmid#YOKen_US
dc.identifier.startpage39en_US
dc.identifier.urihttps://dx.doi.org/10.5152/dcbybd.2015.911
dc.identifier.urihttps://hdl.handle.net/20.500.12395/31861
dc.identifier.volume6en_US
dc.identifier.wosWOS:000219098200004en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.institutionauthorBaldane, Suleyman
dc.language.isotren_US
dc.publisherAVESen_US
dc.relation.ispartofJournal of Medical and Surgical Intensive Care Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectSpontaneous peak expiratory flow rateen_US
dc.subjectspontaneous peak inspiratory flow rateen_US
dc.subjectweaningen_US
dc.subjectpredictoren_US
dc.titleAre spontaneous peak flow rates predictors of weaning?en_US
dc.typeArticleen_US

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