Ratlarda akut yüzme egzersizinin plazma melatonin seviyelerindeki değişiklikler üzerine etkisi
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Dosyalar
Tarih
2005
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Selçuk Üniversitesi Sağlık Bilimleri Enstitüsü
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Gerçekleştirilen çalışmaların sonuçlan egzersizin melatonin sahmmını nasıl etkilediğine dair literatürlerde bîr fikir birliğinin oluşturmadığını göstermektedir. Bu çalışmanın amacı da akut yüzme egzersizi yaptırılan ratlarda egzersizden hemen sonra, egzersizi takiben 24. ve 48. saatlerde plazma melatonin düzeylerindeki değişikliklerin tespit edilebilmesidîr. Araştırmamızın sonuçlan konuyla ilgili bilinenlere ilave katkılar sağlayabilecektir. Bu çalışma S.Ü. Deneysel Tıp Araştırma ve Uygulama Merkezinden (SÜDAM) temin edilen ratlar üzerinde aynı merkezde gerçekleştirildi. Spraque Daw!ey cinsi 40 adet erişkin erkek ratlar kullanılan araştırmada, gruplar şu şekilde oluşturuldu. Grup l, (n-10) Genel Kontrol Grubu: Hiçbir uygulamanın yapılmadığı normal diyetle beslenen grup. Grup 2, («=îO) Yüzme Grubu A: Normal diyetle beslenen ve 30 dakika akut yüzme egzersizi yaptırıldıktan hemen sonra dekapite edilen grup. Grup 3» (ıs=tO) Yüzme Grubu B: Normal diyetle beslenen ve 30 dakika akut yüzme egzersizi yaptırıldıktan 24 saat sonra dekapite edilen grup. Grup 4, (nRlO) Yüzme Grubu C; Normal diyetle beslenen ve 30 dakika akut yüzme egzersizi yaptırıldıktan 48 saat sonra dekapite edilen grup. 31 Çalışmada kullanılan hayvanların tamamından dekapitasyonla alınan kan örneklerinde plazma melatonin düzeyleri RIA yöntemiyle tayin edildi. Plazma melatonin düzeyleri gruplar arasında mukayese edildiğinde Grup 3 en yüksek plazma melatonin düzeylerine sahipti (p<0.01). Grup l (kontrol) ile grup 4'ün plazma melatonin düzeyleri birbirinden farklı değildi. Grup 2 ise en düşük plazma melatonin seviyelerine sahipti (p<0.01) Gerçekleştirdiğimiz çalışmanın sonuçlan akut yüzme egzersizinden hemen sonra azalan plazma melatonin düzeylerinin egzersizden 24 saat sonra önemli ölçüde yükseldiği, 48 saat sonra ise istirahat değerlerine döndüğünü göstermektedir. Çalışmamızda ortaya konulan bulgular bu konuda bilinenlere ilave katkılar sağlayabilecek düzeydedir.
The results of previous studies showed that is not agreameot in literature how exercise affect plasma melatonin levels. The aim of present study was also investigate plasma melatonin levels in performing acute swimming exercise rat, just after exercising and 24th and 4Sth hours, respectively. The results of our research may be put in new information on present literature. The present study was performed in Selçuk University, Experimental Medicine and Research Center, and rat were taken mentioned center. This study was performed on 40 male Spraque-Dawley rat. Groups were formed as follows: Group 1 (n~10), Intact control group: This group was fed a normal diet and was not any application. Group 2 (n=40): Swimming group A: The animals were fed by normal diet and decapited after 30 minutes swimming exercise. Group 3 (n=10): Swimming group B: This group was fed a normal diet and performed 30 minutes swimming exercise and decapited at 24th hour after swimming exercise. Group 4 (n=îö): Swimming group C: This group was fed by normal diet and performed 30 minutes swimming exercise and decapited at 48th hour after swimming exercise. Plasma melatonin levels were measured by R1A methods in blood of decapited animals. When the compared of plasma melatonin levels in groups, gioup 3 has got the biggest plasma melatonin levels (p<0.01 ). Group 1 (intact control) and group 4 were not different each other. Group 2 has got the lowest plasma melatonin levels (p<0.Ql). The present study shows mat plasma melatonin levels reduce just after acute swimming exercise, but significicantly increases after 24 hour exercise and return resting levels at 48th 33 hour of exercise. The results of our research are significant as much as to be put in new information on present literature.
The results of previous studies showed that is not agreameot in literature how exercise affect plasma melatonin levels. The aim of present study was also investigate plasma melatonin levels in performing acute swimming exercise rat, just after exercising and 24th and 4Sth hours, respectively. The results of our research may be put in new information on present literature. The present study was performed in Selçuk University, Experimental Medicine and Research Center, and rat were taken mentioned center. This study was performed on 40 male Spraque-Dawley rat. Groups were formed as follows: Group 1 (n~10), Intact control group: This group was fed a normal diet and was not any application. Group 2 (n=40): Swimming group A: The animals were fed by normal diet and decapited after 30 minutes swimming exercise. Group 3 (n=10): Swimming group B: This group was fed a normal diet and performed 30 minutes swimming exercise and decapited at 24th hour after swimming exercise. Group 4 (n=îö): Swimming group C: This group was fed by normal diet and performed 30 minutes swimming exercise and decapited at 48th hour after swimming exercise. Plasma melatonin levels were measured by R1A methods in blood of decapited animals. When the compared of plasma melatonin levels in groups, gioup 3 has got the biggest plasma melatonin levels (p<0.01 ). Group 1 (intact control) and group 4 were not different each other. Group 2 has got the lowest plasma melatonin levels (p<0.Ql). The present study shows mat plasma melatonin levels reduce just after acute swimming exercise, but significicantly increases after 24 hour exercise and return resting levels at 48th 33 hour of exercise. The results of our research are significant as much as to be put in new information on present literature.
Açıklama
Anahtar Kelimeler
Rat, Plazma melatonin, Plasma melatonin, Yüzme, Swimming
Kaynak
WoS Q Değeri
Scopus Q Değeri
Cilt
Sayı
Künye
Uzun, A. (2005). Ratlarda akut yüzme egzersizinin plazma melatonin seviyelerindeki değişiklikler üzerine etkisi. Selçuk Üniversitesi, Yayımlanmış yüksek lisans tezi, Konya.
