Sistemik brusellozlu hastalarda somatosensoryal evok potansiyeller
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Tarih
1999
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info:eu-repo/semantics/openAccess
Özet
Brusettoz, brusella cinsi bakterilerin neden oldugu bir zoonozdur. Brusellozda santral sinir sistemi tutulumu oldukga nadirdir. Sinir sistemi tutulumunda lezyonun yerine bagh olarak menenjit, meningoensefalit, perife-rik noropati, kranyal sinir tutulumu gorWlebilir. Tani serolojik testier, evok potansiyelleri, beyin omurilik sivi-sinda brusella aglutinasyon testi ve mikroorganizmanm uretilmesi ile konabilir. Bu cahsmada 32 sistemik brusellozlu hasta ve 30 saghkh kiside somatosensoryal evok potansiyelleri (SEP) cahstldi. Kontrol grubunun ta-mammda normal latansh SEP elde edildi. Hastalann 9'unda (%28) SEP elde edilemedi. SEP elde edilen hasta-lartn latans ortalamalan da kontrolgrubuna gore uzun bulundu (p0.05). Bu sonuglar sistemik brusellozlu hastalarda subklinik norolojik tutulumdan siXphelenildiginde dolayh bir bulgu olarak SEP'in yol gosterebilece-gini dusiindurdii.
Brucellosis is an infectious disease of animals transmitted to humans either through contact with infected ani¬mals or by ingestion of their products, particularly infected milk or milk products. Neurobrucellosis is among the chronic manifestations of the disease and afflicts approximately 5% of patients with brucellosis. The clini¬cal presentations of neurobrucellosis may be acute meningoencephalitis, meningomyelitis, central nervous sys¬tem demyelination, neuropathy, myelopathy and radiculopathy. Brucellosis is diagnosed by performing the quantified standard tube agglutination test. The test may be performed on serum and CSF. Magnetic rezonans imaging and computarize tomograpy may assist in visualising the structural abnormalites. In this study soma-tosensorial evokedpotantials were evaluated in thirty-two patients who have brucellosis and thirty healthy sub¬jects.'SEP latencies were found to be normal in control group, and in 9 (28%) of the patients SEPs could not be elicited. Avarage latencies of the patients in whom SEPs could be elicited were found to be prolonged than tho¬se of the control group (p<0.05). We suggest that in systemic brucellosis subclinical neurological deficits can be evaluated with the use of SEPs.
Brucellosis is an infectious disease of animals transmitted to humans either through contact with infected ani¬mals or by ingestion of their products, particularly infected milk or milk products. Neurobrucellosis is among the chronic manifestations of the disease and afflicts approximately 5% of patients with brucellosis. The clini¬cal presentations of neurobrucellosis may be acute meningoencephalitis, meningomyelitis, central nervous sys¬tem demyelination, neuropathy, myelopathy and radiculopathy. Brucellosis is diagnosed by performing the quantified standard tube agglutination test. The test may be performed on serum and CSF. Magnetic rezonans imaging and computarize tomograpy may assist in visualising the structural abnormalites. In this study soma-tosensorial evokedpotantials were evaluated in thirty-two patients who have brucellosis and thirty healthy sub¬jects.'SEP latencies were found to be normal in control group, and in 9 (28%) of the patients SEPs could not be elicited. Avarage latencies of the patients in whom SEPs could be elicited were found to be prolonged than tho¬se of the control group (p<0.05). We suggest that in systemic brucellosis subclinical neurological deficits can be evaluated with the use of SEPs.
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6
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4
