The ability and utility of diffusion-weighted magnetic resonance imaging with different ‘b’ values in the differentiation of benign from malignant lung lesions

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dc.contributor.authorElbir F.Ş.
dc.contributor.authorÖztürk M.
dc.contributor.authorDoğan S.
dc.date.accessioned2020-03-26T20:20:56Z
dc.date.available2020-03-26T20:20:56Z
dc.date.issued2020
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractPurpose: To evaluate the ability and the utility of diffusion-weighted magnetic resonance imaging (MRI) with different ‘b’ values to visualise benign and malignant lung lesions, and to determine which ‘b’ value (b = 300, 500, or 1000 s/mm2) was most useful in differentiating benign from malignant lung lesions. Material and methods: A total of 100 patients (28 women, 72 men; mean age = 57.19 ± 13.44 years; age range = 20-83 years). Diffusion-weighted imaging (DWI) was obtained with ‘b’ values of 300, 500, and 1000 s/mm². The signal intensity of lesions on DWI images was analysed, and the apparent diffusion coefficient (ADC) values of the lesions were calculated. MRI was performed in all patients after having presented at our department for thoracic computed tomography for various reasons. Results: A statistically significant difference in DWI signal scores was detected between benign and malignant lesions for all ‘b’ factors (p < 0.0001 for each). The sensitivity and specificity were 95% and 64%, respectively, when a score of 3 for b = 300 s/mm²; 90% and 69%, respectively, when a score of 3 for b = 500 s/mm²; and 84% and 74%, respectively, when a score of 3 for b = 1000 s/mm². ADC values showed significant differences between benign and malignant lesions for all ‘b’ factors (p < 0.0001 for each). Conclusions: Using ‘b’ values of 300, 500, and 1000 s/mm², DWI signal intensity scores and ADC values are effective methods for the differential diagnosis of malignant and benign pulmonary lesions. © Pol J Radiol 2020.en_US
dc.identifier.doi10.5114/pjr.2020.92834en_US
dc.identifier.endpagee20en_US
dc.identifier.issn1733134Xen_US
dc.identifier.issue1en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpagee14en_US
dc.identifier.urihttps://dx.doi.org/10.5114/pjr.2020.92834
dc.identifier.urihttps://hdl.handle.net/20.500.12395/38704
dc.identifier.volume85en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherMedical Science Internationalen_US
dc.relation.ispartofPolish Journal of Radiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectB factoren_US
dc.subjectDiffusion-weighted magnetic resonance imagingen_US
dc.subjectPulmonary lesionsen_US
dc.titleThe ability and utility of diffusion-weighted magnetic resonance imaging with different ‘b’ values in the differentiation of benign from malignant lung lesionsen_US
dc.typeArticleen_US

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