Tip II diabetes mellituslu olgularda sigara, kan basıncı, kardiyovasküler hastalık ve nefropati ile retinopati arasındaki ilişkiler
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2004
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info:eu-repo/semantics/openAccess
Özet
Amaç: Tip II Diabetes Mellitus'lu olgularda diabetik retinopati gelişimi ve ağırlığı üzerine bazı sistemik risk faktörlerinin etkisinin araştırılması. Gereç ve Yöntem: Tip II DM'lu 150 olgu (79 kadın, 71 erkek) çalışmaya dahil edildi. Tip II DM'lu olgularda cinsiyet, yaş, sistolik kan basıncı (SKB), diastolik kan basıncı (DKB), kardiyovasküler hastalık (KVH), nefropati (NP) ve sigara kullanımı gibi risk faktörlerinin diabetik retinopati (DR) gelişimi ve ağırlığı üzerine olan etkileri araştırıldı. Bulgular: Olguların yaşları 36 ile 83 arasında değişmekte idi (58.1713.35 yıl). Olguların 56'sında (%37.3) nonproliferatif diabetik retinopati (NPDR), 44'ünde (%29.3) proliferatif diabetik retinopati (PDR) olmak üzere toplam 100 (%66.7) olguda DR vardı. DR'nin insidansı kadınlarda %67.1 iken erkeklerde %66.2 idi. DR'si bulunan olgularda SKB, DKB, KVH, NP ve sigara kullanımı ile DR gelişimi ve ağırlığı arasında istatistiksel olarak anlamlı ilişki vardı (p0.05). Bu risk faktörlerinden SKB lojistik regresyon analizi sonucunda bağımsız risk faktörü olarak tespit edildi. Ancak risk faktörlerinden cinsiyet ve yaş ile DR gelişimi ve ağırlığı arasında istatistiksel olarak anlamlı bir ilişki bulunmadı (p0.05). Sonuç: Diabetli olgularda DR gelişimini ve ağırlığını olumsuz olarak etkileyebilen SKB ve sigara kullanımı gibi risk faktörlerinin kontrol edilmesiyle DR gelişimi ve ağırlığı üzerine olan olumsuz etkilerini ortadan kaldırabiliriz.
Purpose: To evaluate effects of some risk factors on the development and progression of diabetic retinopathy (DR) in patients with type II diabetes mellitus (DM). Materials and Method: This study included 150 patients with type II DM (79 male, 71 female). We evaluated the effects of the risk factors such as sex, age, systolic blood pressure (SBP), diastolic blood pressure (DBP), cardiovascular disease (CVD), nephropathy (NP) and smoking on the development and progression of DR in patients with type II diabetes mellitus (DM). Results: The age of patients were between 36-83 years (58.1±13.3). One hundred out of 150 patients (66.7%) had DR. Fifty-six of these 100 patients (37.3%) had nonproliferative diabetic retinopathy (NPDR), and the remaning patients (29.3%) had proliferative diabetic retinopathy (PDR). The incidence of DR was 67.1% in females and 66.2% in males. Significant relationship was found between the development and progression of DR and risk factors such as SBP, DBP, CVD, NP and smoking (p<0.05). SBP was found as independent risk factors. There was no significant relationship between the development and progression of DR and risk factors such as sex and age (p>0.05). Conclusion: The control of the risk factors, SBP and smoking effecting on DR in patients with diabetes mellitus, will be helpfull in inhibition and delay of DR development.
Purpose: To evaluate effects of some risk factors on the development and progression of diabetic retinopathy (DR) in patients with type II diabetes mellitus (DM). Materials and Method: This study included 150 patients with type II DM (79 male, 71 female). We evaluated the effects of the risk factors such as sex, age, systolic blood pressure (SBP), diastolic blood pressure (DBP), cardiovascular disease (CVD), nephropathy (NP) and smoking on the development and progression of DR in patients with type II diabetes mellitus (DM). Results: The age of patients were between 36-83 years (58.1±13.3). One hundred out of 150 patients (66.7%) had DR. Fifty-six of these 100 patients (37.3%) had nonproliferative diabetic retinopathy (NPDR), and the remaning patients (29.3%) had proliferative diabetic retinopathy (PDR). The incidence of DR was 67.1% in females and 66.2% in males. Significant relationship was found between the development and progression of DR and risk factors such as SBP, DBP, CVD, NP and smoking (p<0.05). SBP was found as independent risk factors. There was no significant relationship between the development and progression of DR and risk factors such as sex and age (p>0.05). Conclusion: The control of the risk factors, SBP and smoking effecting on DR in patients with diabetes mellitus, will be helpfull in inhibition and delay of DR development.
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11
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4
