Selenyumun Koyunlarda Bazı Bi?yoki?myasal Parametreler Üzeri?ne Etki?leri?ni?n Araştırılması
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Dosyalar
Tarih
2001 Nisan
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Selçuk Üniversitesi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Bu çalışma, deneysel olarak selenyum zehirlenmesi oluşturulan koyunlarda serum aspartat transaminaz (AST), alanin transaminaz (ALT), g-glutamil transpeptidaz (GGT), alkalin fosfataz (ALP), laktik dehidrojenaz (LDH), kreatin fosfokinaz (CPK), total bilirubin (TB), direk bilirubin (DB), total protein (TP), trigliserid, albümin ve glikoz düzeylerinde meydana gelen değişiklikleri belirlemek amacıyla yapıldı. Araştırmada ağırlıklan 50-55 kg arasında 18 adet koyun kullanıldı. Selenyum kas içi yolla 0.2 ve 0.6 mg/kg dozlarında verildi. Kan ömekleri 0.5, 1, 3, 6, 12, 24, 48, 72, 120 ve 240. saatlerde alındı ve bu ömekler AST, ALT, GGT, ALP, LDH, CPK, TB, DB TP, trigliserid, albümin ve glikoz yönünden incelendi. Sonuç olarak, deneysel yolla oluşturulan selenyum zehirlenmesinde selenyumun koyunların serum AST, ALT, LDH, CPK, TB, DB ve TP düzeylerini artırdığı, buna karşılık glikoz düzeylerini ise azalttığı belirlendi.
This study was carried out to investigate the changes in the levels of serum aspartate transaminase (AST), alanine transaminase (ALT), g-glutamyl transpeptidase (g-GT), alkaline phosphatase (ALP), lactic dehydrogenase (LDH), creatine phosfokinase (CPK), total bilirubin (TB), direct bilirubin (DB), total protein (TP), triglyceride, albumin and glucose in sheep experimentally poisoned with selenium. In this study, 18 sheep at the weight of 50-55 kg were used. Selenium was given intramuscularly at the doses of 0.2 and 0.6 mg/kg. The blood samples were collected at 0.5, 1, 3, 6, 12, 24, 48, 72, 120 and 240th hours. These samples were analysed for the levels of AST, ALT, GGT, ALP, LDH, CPK, TB, DB, TP, triglyceride, albumin and glucose. In conclusion, selenium caused to increase the levels of AST, ALT, ALP, LDH, CPK, TB, DB and TP in serum of sheep with the experimentally induced selenium poisoning. In contrast, selenium decreased the levels of glucose in serum of sheep.
This study was carried out to investigate the changes in the levels of serum aspartate transaminase (AST), alanine transaminase (ALT), g-glutamyl transpeptidase (g-GT), alkaline phosphatase (ALP), lactic dehydrogenase (LDH), creatine phosfokinase (CPK), total bilirubin (TB), direct bilirubin (DB), total protein (TP), triglyceride, albumin and glucose in sheep experimentally poisoned with selenium. In this study, 18 sheep at the weight of 50-55 kg were used. Selenium was given intramuscularly at the doses of 0.2 and 0.6 mg/kg. The blood samples were collected at 0.5, 1, 3, 6, 12, 24, 48, 72, 120 and 240th hours. These samples were analysed for the levels of AST, ALT, GGT, ALP, LDH, CPK, TB, DB, TP, triglyceride, albumin and glucose. In conclusion, selenium caused to increase the levels of AST, ALT, ALP, LDH, CPK, TB, DB and TP in serum of sheep with the experimentally induced selenium poisoning. In contrast, selenium decreased the levels of glucose in serum of sheep.
Açıklama
Anahtar Kelimeler
Selenyum, koyun, zehirlenme, biyokimyasal parametre, Selenium, sheep, poisoning, biochemical parameters
Kaynak
Eurasian Journal of Veterinary Sciences
WoS Q Değeri
Scopus Q Değeri
Cilt
17
Sayı
3
Künye
Pirinçci, İ., Ateşşahin, A., Elitok, B., (2001). Selenyumun Koyunlarda Bazı Bi̇yoki̇myasal Parametreler Üzeri̇ne Etki̇leri̇ni̇n Araştırılması. Eurasian Journal of Veterinary Sciences, 17(3), 13-16.