Fetuin-A, inflammation, and coronary artery calcification in hemodialysis patients

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dc.contributor.authorTurkmen K.
dc.contributor.authorGorgulu N.
dc.contributor.authorUysal M.
dc.contributor.authorOzkok A.
dc.contributor.authorSakaci T.
dc.contributor.authorUnsal A.
dc.contributor.authorYildiz A.
dc.date.accessioned2020-03-26T18:22:14Z
dc.date.available2020-03-26T18:22:14Z
dc.date.issued2011
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractHemodialysis patients have extremely increased cardiovascular mortality. Vascular calcification, inflammation, and low serum fetuin-A levels are implicated for increased mortality. In this study, relationship between coronary artery calcification, inflammation, and serum fetuin-A levels were investigated. Seventy-eight hemodialysis patients (38 male, 40 female, mean age: 52±14.5 years) were included. All patients were on dialysis for more than 6 months. Coronary artery calcium scores (CACS) are determined by electron-beam computed tomography. Serum CRP, IL-1?, IL-6, TNF-?, and serum fetuin-A levels were measured. Mean CACS value was 488.5±94.5. Serum fetuin-A levels were negatively correlated with CACS (r. -0.30, P=0.009). Patients are divided into two groups according to total CACS value; group 1 (CACS<10), group 2 (CACS?10). There was a statistically significance difference in fetuin-A levels between CACS group 1 and group 2 (P=0.001). In this study, serum fetuin-A levels were associated with total CACS. This Fetuin-A may play a role in increased mortality in this group of patients via facilitating CAC.en_US
dc.identifier.doi10.4103/0971-4065.82128en_US
dc.identifier.endpage94en_US
dc.identifier.issn0971-4065en_US
dc.identifier.issue2en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage90en_US
dc.identifier.urihttps://dx.doi.org/10.4103/0971-4065.82128
dc.identifier.urihttps://hdl.handle.net/20.500.12395/27236
dc.identifier.volume21en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.relation.ispartofIndian Journal of Nephrologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectFetuin-Aen_US
dc.subjecthemodialysisen_US
dc.subjectinflammationen_US
dc.subjectvascular calcificationen_US
dc.titleFetuin-A, inflammation, and coronary artery calcification in hemodialysis patientsen_US
dc.typeArticleen_US

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