Hastane infeksiyonu etkeni pseudomonas suşlarının antibiyotiklere duyarlılıkları
Küçük Resim Yok
Tarih
2009
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Bu çalışmada 2008 yılında prospektif ve aktif sürveyans yöntemi ile izlenen ve hastane infeksiyonu tanısı alan hastaların klinik örneklerinden izole edilen 159 Pseudomonas suşunun antibiyotiklere duyarlılıkları belirlenmiştir. Kolistine % 100, piperasilin/tazobaktama % 77, amikasine % 76, sefoperazon/sulbaktama % 68, seftazidime % 64, netilmisine % 62, sefepime % 57, siprofloksasine % 56, aztreonama % 52, levoşoksasine % 50, gentamisine % 48, imipeneme % 46 ve sefotaksime % 17 oranında duyarlılık saptanmıştır. Buna göre kolistin, piperasilin/tazobaktam, amikasin, sefoperazon/sulbaktam ve seftazidim diğer antibiyotiklere göre daha etkili bulunmuştur. Antibiyotik direncinin hastaneden hastaneye hatta servisten servise değişiklik gösterebilmesi nedeniyle, özellikle ampirik tedavi gereken durumlarda bu tür dirençli bakterilerin duyarlılık oranlarının bilinmesi gereklidir.
In this study antibiotic susceptibilities of 159 Pseudomonas strains isolated from clinical specimens of patients with nosocomial infections in 2008 were reported. The antibiotic susceptibility rates of the organisms were found to be 100 % for colistin, 77 % for piperacillin/tazobactam, 76 % for amikacin, 68 % for cefoperazone/sulbactam, 64 % for ceftazidime, 62 % for netilmicin, 57 % for sefepime, 52 % for aztreonam, 56 % for ciprofloxacin, 50 % for levoşoxacin, 48 % for gentamicin, 46 % for imipenem and 17 % for cefotaxime. The results indicate that colistin, piperacillin/tazobactam, amikacin, cefoperazone/sulbactam and ceftazidime are more active agents than other antibiotics. Because of resistance rates to antibiotics may vary from hospital to hospital or even from clinic to clinic, it is essential that susceptibility rates of such resistant bacteria should be known especially in situations where empirical treatment is requi-red.
In this study antibiotic susceptibilities of 159 Pseudomonas strains isolated from clinical specimens of patients with nosocomial infections in 2008 were reported. The antibiotic susceptibility rates of the organisms were found to be 100 % for colistin, 77 % for piperacillin/tazobactam, 76 % for amikacin, 68 % for cefoperazone/sulbactam, 64 % for ceftazidime, 62 % for netilmicin, 57 % for sefepime, 52 % for aztreonam, 56 % for ciprofloxacin, 50 % for levoşoxacin, 48 % for gentamicin, 46 % for imipenem and 17 % for cefotaxime. The results indicate that colistin, piperacillin/tazobactam, amikacin, cefoperazone/sulbactam and ceftazidime are more active agents than other antibiotics. Because of resistance rates to antibiotics may vary from hospital to hospital or even from clinic to clinic, it is essential that susceptibility rates of such resistant bacteria should be known especially in situations where empirical treatment is requi-red.
Açıklama
Anahtar Kelimeler
Farmakoloji ve Eczacılık
Kaynak
ANKEM Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
23
Sayı
3
