Absence of Anca in Behçet's Syndrome with Large Vessel Involvement

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Küçük Resim

Tarih

2001

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Thieme Medical Publishers, Inc.

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

The aim of this study was to examine the prevalence of anti-neutrophil cytoplasmic antibodies (ANCA) in patients with Behcet's syndrome (BS) with large vessel involvement. The sera of 48 consecutive patients with BS with large vessel involvement, seven patients with Wegener granulomatosis (WG), and 10 healthy staff were studied for the presence of the cytoplasmic (c) and perinuclear (p) pattern of ANCA by indirect immunofluoresance (IIF). The sera were also examined for antibodies against proteinase 3 (anti-PR3) and myeloperoxidase (anti-MPO) by enzyme-linked immunosorbent assay (ELISA). None of the sera from the patients with BS and healthy controls had detectable ANCAs, while all positive control sera from patients with WG showed ANCA positivity in some form. This study confirms that there are no detectable ANCAs in patients with BS with large vessel involvement by IIF and ELISA tests.

Açıklama

Anahtar Kelimeler

Kaynak

International Journal of Angiology

WoS Q Değeri

Scopus Q Değeri

Q3

Cilt

10

Sayı

Künye

Tunç, R., Özbakır, F., Çağlayan, A., Altıparmak, M. R., Yargan, P., Fresko, İ., Yazıcı, H., (2001). Absence of ANCA in Behçet's Syndrome with Large Vessel Involvement. International Journal of Angiology, (10), 260-262. Doi: 10.1007/BF01637045