The role of ischemia modified albumin in the evaluation of hemodynamic changes in the splanchnic area during laparoscopic cholecystectomy [Laparoskopik kolesistektomi süresince splanknik sahadaki hemodinamik de?işikliklerin de?erlendirilmesinde iskemi modifiye albuminin rolü]

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dc.contributor.authorKöksal H.
dc.contributor.authorKurban S.
dc.contributor.authorŞahin M.
dc.date.accessioned2020-03-26T18:05:51Z
dc.date.available2020-03-26T18:05:51Z
dc.date.issued2010
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractPurpose: Elevation of intraabdominal pressure by means of gas insufflation produces hemodynamic disturbances in the peritoneal viscera, leading to splanchnic ischemia. Recently, ischemia modified albumin (IMA) has been used to investigate conditions such as myocardial and skeletal muscle ischemia. The purpose of this clinical investigation is to determine the role of IMA in the evaluation of alterations in blood flow of the splanchnic area and abdominal viscera during laparoscopic cholecystectomy. Patients and Methods: Twenty two patients (F/M: 21/1) undergoing laparoscopic cholecystectomy (Group I) and 10 patients (F/M: 7/3) undergoing various surgical procedures under general an- estheasia (Group II) were studied. No patient had any cardiovascular disease. Blood samples for IMA were collected at preoperative and intraoperative periods. A rapid, colorimetric assay was used to measure serum IMA levels. Results: In Group I, the preoperative and intraoperative IMA levels were 0.59±0.16 absorbance units (ABSU) and 0.74±0.17 ABSU, respectively. The intraoperative IMA levels were higher than the preoperative levels (p=0.025). In Group II, the preoperative and intraoperative IMA levels were 0.43±0.12 ABSU and 0.52±0.15 ABSU, respectively. The difference was not statistically significant (p=0.22). The intraoperative IMA levels in Group I were higher than Group II (p=0.003).Conclusion: IMA, a new sensitive marker for ischemia, can be helpful for determining alterations in blood flow of the splanchnic area and abdominal viscera during laparoscopic cholecystectomy. cholecystectomy, splanchnic area.en_US
dc.identifier.doi10.5097/1300-0705.UCD.449-10.0en_US
dc.identifier.endpage94en_US
dc.identifier.issn1300-0705en_US
dc.identifier.issue2en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage91en_US
dc.identifier.urihttps://dx.doi.org/10.5097/1300-0705.UCD.449-10.0
dc.identifier.urihttps://hdl.handle.net/20.500.12395/25555
dc.identifier.volume26en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.relation.ispartofTurkish Journal of Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectIschemia modified albuminen_US
dc.subjectLaparoscopicen_US
dc.subjectLaparoscopyen_US
dc.titleThe role of ischemia modified albumin in the evaluation of hemodynamic changes in the splanchnic area during laparoscopic cholecystectomy [Laparoskopik kolesistektomi süresince splanknik sahadaki hemodinamik de?işikliklerin de?erlendirilmesinde iskemi modifiye albuminin rolü]en_US
dc.typeArticleen_US

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