Gece sistolik kan basıncı yükselmelerinin santral hemodinamikler ve arteriyel sertleşme ile ilişkisi
Küçük Resim Yok
Tarih
2012
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
AMAÇ: Bu çalışmanın amacı, gece KB yükselen hastaların santral hemodinamik ve arteriyel sertleşme göstergelerini incelemektir. GEREÇ ve YÖNTEMLER: Bu geriye dönük çalışmada, 252 hipertansif hastanın ayaktan kan basıncı (KB) izlemi Mobil-O-Graph Arteriograph cihazı kullanılarak yapıldı. BULGULAR: Toplam 252 hastanın 174'ü (%69,0) kadın, 78'i (%31) erkek ve yaş ortalamaları 54,514,4 idi. Pearson korelasyon testi uyguladığımızda; sistolik kan basıncında gece düşmeleri, yaş (r-0,169, p0,008), 24 saat (24s) sürecinde periferik direnç (r-0,171, p0,007), gündüz nabız dalga hızı (NDH) (r-0,179, p0,005), gece diyastolik kan basıncında (DKB) azalma (r0,790, p0,001), gece santral sistolik kan basıncı (SKB) (r-0,410, p0,001), gece santral DKB (r-0,387, p0,001), gece arttırma indeksi (Aix@75) (r-0,215, p0,001), gece periferal direnç (r-0,321, p0,001) ile ilişkiliydi. Hastaları sistolik kan basıncında gece düşmelerine göre; kan basıncında %10 ve daha fazla düşme olanlar, %10'dan daha az düşme olanlar ve gece kan basıncı artanlar olmak üzere üç gruba ayırdığımızda gruplar arasında hemoglobin düzeyi (p0,033), gece nabız basıncı (p0,001), gece DKB düşmesi (p0,001), gece Aix@75 (p0,001), gece periferal direnç (0,001) göstergeleri arasında istatistiksel olarak anlamlı fark vardı. SONUÇ: Gece kan basıncı yükselen ve %10'dan az düşen hastaların arteriyel sertleşmeye neden olan geleneksel risk faktörlerinin sıkı izleminin ve hipertansiyon tedavilerinde kronoterapinin kullanılmasının yararlı olabileceğini düşünüyoruz.
OBJECTIVE: The aim of this study was to assess central hemodynamics and parameters of arterial stiffness of cases with nocturnal blood pressure rise. MATERIAL and METHODS: In this retrospective study, ambulatory blood pressure monitoring of 252 hypertensive patients was performed with the Mobil-O-Graph Arteriograph. RESULTS: 174 (%69.0) out of 252 patients were female and 78 (%31) were male and the mean age was 54.5±14.4. When Pearson's correlation test was performed, the nocturnal systolic blood pressure (SBP) decline was associated with age (r-0.169, p0.008), diurnal pulse wave velocity (PWV) (r-0.179, p0.005), nocturnal diastolic blood pressure (DBP) decline (r0.790, p<0.001), nocturnal central SBP (r-0.410, p<0.001), and nocturnal augmentation index (Aix@75) (r-0.215, p0.001). When patients were divided into three groups as 10 % or more nocturnal SBP decline, less than 10 % nocturnal SBP decline and nocturnal SBP increase, there were statistically signifi cant differences regarding nocturnal pulse pressure (p<0.001), nocturnal DBP decline (p<0.001, nocturnal Aix@75 (p<0.001), and nocturnal peripheral resistance (p<0.001). CONCLUSION: We believe that strict follow up of conventional risk factors causing arterial stiffness in patients with less than 10 % nocturnal BP decline or increase and also the use of chronotherapy may be useful.
OBJECTIVE: The aim of this study was to assess central hemodynamics and parameters of arterial stiffness of cases with nocturnal blood pressure rise. MATERIAL and METHODS: In this retrospective study, ambulatory blood pressure monitoring of 252 hypertensive patients was performed with the Mobil-O-Graph Arteriograph. RESULTS: 174 (%69.0) out of 252 patients were female and 78 (%31) were male and the mean age was 54.5±14.4. When Pearson's correlation test was performed, the nocturnal systolic blood pressure (SBP) decline was associated with age (r-0.169, p0.008), diurnal pulse wave velocity (PWV) (r-0.179, p0.005), nocturnal diastolic blood pressure (DBP) decline (r0.790, p<0.001), nocturnal central SBP (r-0.410, p<0.001), and nocturnal augmentation index (Aix@75) (r-0.215, p0.001). When patients were divided into three groups as 10 % or more nocturnal SBP decline, less than 10 % nocturnal SBP decline and nocturnal SBP increase, there were statistically signifi cant differences regarding nocturnal pulse pressure (p<0.001), nocturnal DBP decline (p<0.001, nocturnal Aix@75 (p<0.001), and nocturnal peripheral resistance (p<0.001). CONCLUSION: We believe that strict follow up of conventional risk factors causing arterial stiffness in patients with less than 10 % nocturnal BP decline or increase and also the use of chronotherapy may be useful.
Açıklama
Anahtar Kelimeler
Cerrahi
Kaynak
Türk Nefroloji Diyaliz ve Transplantasyon Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
21
Sayı
3
