Ghrelin, resistin and leptin levels in patients with metabolic syndrome [Metabolik sendromlu hastalarda grelin, rezistin ve leptin düzeyleri]

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dc.contributor.authorKoç F.
dc.contributor.authorTokaç M.
dc.contributor.authorKocabaş V.
dc.contributor.authorKaya C.
dc.contributor.authorBüyükbaş S.
dc.contributor.authorErdem S.
dc.contributor.authorKaraba? T.
dc.date.accessioned2020-03-26T18:22:03Z
dc.date.available2020-03-26T18:22:03Z
dc.date.issued2011
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractAim: This study was designed to compare the fasting ghrelin, leptin and resistin levels between metabolic syndrome (MS) patients with healthy controls. Method: This trial was performed on 21 patients with MS (7 men; mean age, 44±4 years) and 17 healthy controls (8 men; mean age, 43±3 years). Diagnosis of MS was defined based on National Cholesterol Education Program (NCEP) Adult Treatment Panel (ATP) III criteria. Patients meeting at least 3 of the MS criteria, with a body mass index (BMI) ?30 kg/m2 were included in the MS group. Among healthy volunteers, those with a BMI<30 kg/m2 were selected as the control group. Plasma ghrelin, serum leptin and resistin concentrations were measured by ELISA method. Result: Ghrelin levels were similar between MS and control groups. There was a negative correlation detected between ghrelin levels with BMI and leptin levels (r=-.54, P=.01 and r=-.56, P=.009, respectively). Resistin levels were found similar between MS with control groups. Leptin levels were significantly higher at the MS group than control group (35±17 ng/ml vs. 14±8 ng/ml, P=.001). Leptin levels had a positive correlation with BMI (r=.56; P=.008). Conclusion: We have demonstrated that leptin levels in MS group were higher than control group. However, ghrelin and resistin levels were similar to control group. In addition, we have showed leptin levels has a positive correlation with BMI and a negative correlation with ghrelin levels.en_US
dc.identifier.endpage97en_US
dc.identifier.issn1304-3889en_US
dc.identifier.issue2en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage92en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/27101
dc.identifier.volume8en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.relation.ispartofEuropean Journal of General Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectGhrelinen_US
dc.subjectLeptinen_US
dc.subjectMetabolic syndromeen_US
dc.subjectObesityen_US
dc.subjectResistinen_US
dc.titleGhrelin, resistin and leptin levels in patients with metabolic syndrome [Metabolik sendromlu hastalarda grelin, rezistin ve leptin düzeyleri]en_US
dc.typeArticleen_US

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