Endometrium kanseri olan hastalarda uyku kalitesi ve tedavinin etkisi
Küçük Resim Yok
Tarih
2017
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Uyku bozuklukları jinekolojik kanserli hastaların %54,9'unu etkilemektedir ve önemli bir sağlık sorunu oluşturmaktadır. Tedavi yöntemlerinin uyku kalitesine olan etkisi net değildir. Bu çalışma endometrium kanseri tedavisi alan hastalarda uyku kalitesinin değerlendirilmesi ve tedavi yöntemlerinin uyku kalitesine etkisini karşılaştırmayı amaçlamaktadır.Gereç ve Yöntemler: Hastalar farklı tedavi gruplarında değerlendirildi: (grup 1) cerrahi, (grup 2) cerrahi brakiterapi (BRT), (grup 3) cerrahi eksternalışın radyasyon tedavisi (EBRT) ve (grup 4) cerrahi EBRT BRT kemoterapi. Uyku kalitesi Pittsburgh Uyku Kalitesi İndeksi (PSQI) anket formu kullanılarak değerlendirildi. Bu form katılımcılar tarafında ilk olarak tedavi öncesi dolduruldu. İkinci ölçüm her bir tedavi, yönteminin bitiminde 1 ay sonra ve sonrasında 3. ve 6. aylarda yapıldı. PSQI skorları farklı klinik gruplarda ve farklı ölçüm zamanlarında karşılaştırıldıBulgular: Bu çalışmaya 114 katılımcı dahil olmuştur. Çalışma grubunu ortalama yaşı 58,111'dir. Hastaların 53'ü (%46,5) sadece cerrahi, 14'ü (%12,3) cerrahi BRT, 12'si (%10,5) cerrahi BRT eksternal radyoterapi ve 35'i (%30,7) hasta kemoradyoterapi tedavisi aldı. Başlangıçta, 28 (%24,6) hasta düşük uyku kalitesi bildirdi. Ortalama PSQI skoru ikinci ölçümde maksimuma ulaştı ve takipler boyunca azaldı. PSQI skorundaki değişim anlamlı bulundu (p0,001). Üçüncü ölçümde gruplar arası karşılaştırmada anlamlı farklılık saptandı. Üçüncü ve dördüncü grupların ortalama skorları başlangıç skorlarında anlamlı yüksek saptandı (p0,008). Dördüncü ölçümde tedavi yöntemleri içerisinde uyku kalitesine en belirgin etki kombine kemoradyoterapi alan hasta grubunda gözlemlendi.Sonuç: Endometrium kanseri tedavisi alan hastaların birçoğu düşük uyku kalitesi sorunu yaşamaktadır. Hastaların yaşam kalitesini artırmak için bu durum her muayenede sorgulanmalı ve hastanın ihtiyaçlarının karşılayacak kişiye özel tedavi planları yapılmalıdır. Bu durumun uzun dönem sonuçlarının değerlendirilmesi için daha fazla çalışmaya ihtiyaç vardır
Objective: Sleep disorders affect 54.9% of gynaecologic cancer survivors. The effect of treatment methods on sleep quality is not clear. This study evaluated the sleep quality of survivors of endometrial cancer and compared the effects of different treatments on sleep quality.Materials and Methods: Patients were categorised as surgery (group 1), surgery brachytherapy (BRT) (group 2), surgery external beam radiation therapy (EBRT) (group 3), and surgery EBRT BRT chemotherapy (group 4). Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI) questionnaire. The PSQI was completed by the participants before surgery, 1, 3, and 6 months after each treatment was completed. The PSQI scores were compared between the different measurement times and different study groups.Results: This study enrolled 114 patients with a mean age of 58.111 years. The number of participants in each group was 53 (46.5%), 14 (12.3%), 12 (10.5%), and 35 (30.7%), respectively. At baseline, 28 (24.6%) patients reported poor sleep quality. The mean PSQI score reached the maximum level at the second measurement and decreased slightly during follow-up and the change in the PSQI score was significant (p0.001). Group 3 and group 4 had significantly higher scores from baseline (p0.008). At time point 3, the differences between the groups were significant. At time point 4, the most prominent effect of treatment on sleep quality was observed in patients with combined chemo-radiotherapy when compared with the other study groups.Conclusion: Most survivors of endometrial cancer are affected by poor sleep quality during their treatment. To improve these patients’ quality of life, this disorder must be considered at each visit and tailored care plans should be developed to meet the women’s needs. Further studies are needed to evaluate the long-term results of sleep quality on patients with endometrial cancer
Objective: Sleep disorders affect 54.9% of gynaecologic cancer survivors. The effect of treatment methods on sleep quality is not clear. This study evaluated the sleep quality of survivors of endometrial cancer and compared the effects of different treatments on sleep quality.Materials and Methods: Patients were categorised as surgery (group 1), surgery brachytherapy (BRT) (group 2), surgery external beam radiation therapy (EBRT) (group 3), and surgery EBRT BRT chemotherapy (group 4). Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI) questionnaire. The PSQI was completed by the participants before surgery, 1, 3, and 6 months after each treatment was completed. The PSQI scores were compared between the different measurement times and different study groups.Results: This study enrolled 114 patients with a mean age of 58.111 years. The number of participants in each group was 53 (46.5%), 14 (12.3%), 12 (10.5%), and 35 (30.7%), respectively. At baseline, 28 (24.6%) patients reported poor sleep quality. The mean PSQI score reached the maximum level at the second measurement and decreased slightly during follow-up and the change in the PSQI score was significant (p0.001). Group 3 and group 4 had significantly higher scores from baseline (p0.008). At time point 3, the differences between the groups were significant. At time point 4, the most prominent effect of treatment on sleep quality was observed in patients with combined chemo-radiotherapy when compared with the other study groups.Conclusion: Most survivors of endometrial cancer are affected by poor sleep quality during their treatment. To improve these patients’ quality of life, this disorder must be considered at each visit and tailored care plans should be developed to meet the women’s needs. Further studies are needed to evaluate the long-term results of sleep quality on patients with endometrial cancer
Açıklama
Anahtar Kelimeler
Cerrahi
Kaynak
Turkish Journal of Obstetrics and Gynecology
WoS Q Değeri
Scopus Q Değeri
Cilt
14
Sayı
4
