Serum gastrin in dogs with acute or chronic gastritis and positive or negative for Helicobacter sp in the stomach

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dc.contributor.authorGuzelbektes, Hasan
dc.contributor.authorCoskun, Alparslan
dc.contributor.authorOrtatatli, Mustafa
dc.contributor.authorSen, Ismail
dc.date.accessioned2020-03-26T17:27:44Z
dc.date.available2020-03-26T17:27:44Z
dc.date.issued2008
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe relationship between gastrin levels and presence of Helicobacter-like organisms (HLO) in dogs with acute or chronic gastritis was investigated. For this purpose, a total of 52 crossbred Kangal Dogs aging 2-5 years were used; including 12 dogs with acute gastritis, 25 dogs with chronic gastritis, and 15 healthy dogs. Blood samples were collected from the vena cephalica. Serum gastrin levels were measured using commercial competitive binding radioimmunoassay. HLO were found in 64%, 58.3%, and 60% of animals with chronic gastritis or acute gastritis, and controls, respectively. The gastrin levels in dogs with chronic gastritis were higher than in those with acute gastritis and controls. There were no significant differences between the gastrin levels in all groups, with regard to HLO positive versus HLO negative dogs. In conclusion, HLO incidence was generally found in high levels in all the dogs. However, HLO did not primarily affect the stomach mucosal damage. In the mean time, there was no relation between the levels of serum gastrin in dogs with gastritis, either being HLO positive or negative. The results of the study showed that higher gastrin levels in dogs with gastritis were related to severe gastric lesions and mucosal damage.en_US
dc.description.sponsorshipUniversity of Selcuk, Scientific Research Project Coordinator OfficeSelcuk Universityen_US
dc.description.sponsorshipThis study was partly supported by the University of Selcuk, Scientific Research Project Coordinator Office.en_US
dc.identifier.endpage361en_US
dc.identifier.issn0042-4870en_US
dc.identifier.issue3en_US
dc.identifier.startpage357en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/22634
dc.identifier.volume52en_US
dc.identifier.wosWOS:000259713100009en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherNATL VETERINARY RESEARCH INSTen_US
dc.relation.ispartofBULLETIN OF THE VETERINARY INSTITUTE IN PULAWYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectdogen_US
dc.subjectHelicobacteren_US
dc.subjectgastritisen_US
dc.subjectgastrinen_US
dc.titleSerum gastrin in dogs with acute or chronic gastritis and positive or negative for Helicobacter sp in the stomachen_US
dc.typeArticleen_US

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