SEVERE HYPERBILIRUBINEMIA DURING FAMILYAL MEDITERRANEAN FEVER ATTACK IN PATIENTS WITH GILBERT'S SYNDROME

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dc.contributor.authorKutlu, Orkide
dc.contributor.authorKeskin, Muharrem
dc.contributor.authorBasturk, Abdulkadir
dc.contributor.authorEcirli, Samil
dc.contributor.authorBilgic, Yilmaz
dc.contributor.authorFisekci Oktar, Sevil
dc.date.accessioned2020-03-26T19:26:19Z
dc.date.available2020-03-26T19:26:19Z
dc.date.issued2016
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractFamilial Mediterranean fever (FMF) is an autosomal recessive disorder characterized by fever and accompanying attacks of serositis. Cytokines such as IL-6, TNF-alpha, IL-1 beta are known to play an active role in FMF pathogenesis. Gilbert's syndrome, is a clinical condition that results indirect hyperbilirubinemia during febrile illness, surgery, vomiting and prolonged fasting period because of inhibition of UDP-glucuronide transferase activity. Increased bilirubin levels during FMF attack is caused suppression of UDP-glucuronide transferase activity by cytokines involved in the pathogenesis of FMF. Here, we report a patient who had serious indirect bilirubin elevation during an attack of FMF.en_US
dc.identifier.endpage132en_US
dc.identifier.issn1305-6433en_US
dc.identifier.issn1305-6441en_US
dc.identifier.issue3en_US
dc.identifier.pmid#YOKen_US
dc.identifier.startpage130en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/33988
dc.identifier.volume79en_US
dc.identifier.wosWOS:000408441500006en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isotren_US
dc.publisherISTANBUL UNIV, FACULTY MEDICINE, PUBLISHING OFFICEen_US
dc.relation.ispartofJOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISIen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectFamilial Mediterranean feveren_US
dc.subjectFMFen_US
dc.subjectindirect bilirubinemiaen_US
dc.subjectGilbert's Syndromeen_US
dc.titleSEVERE HYPERBILIRUBINEMIA DURING FAMILYAL MEDITERRANEAN FEVER ATTACK IN PATIENTS WITH GILBERT'S SYNDROMEen_US
dc.typeArticleen_US

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