Reproducibility of fasting and OGTT-derived insulin resistance indices in normoglycemic women

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dc.contributor.authorCakir M.
dc.contributor.authorSari R.
dc.contributor.authorTosun O.
dc.contributor.authorSaka O.
dc.contributor.authorKarayalcin U.
dc.date.accessioned2020-03-26T17:05:32Z
dc.date.available2020-03-26T17:05:32Z
dc.date.issued2006
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractOBJECTIVE: To determine the reproducibility of fasting and oral glucose tolerance test (OGTT) -derived insulin-resistance (IR) indices in obese and nonobese women. METHODS: Twenty-one obese (BMI 37.7±6.3 kg/m2) and 14 nonobese (BMI 21.5±1.0 kg/m2) age-matched, healthy, premenopausal women were included in the study. An OGTT was performed twice, with a 1-week interval between tests. IR was calculated from both fasting and post-load glucose and insulin values, using some of the more well-known indices. RESULTS: When the 2 groups were evaluated separately, all indices were found to be reproducible in obese subjects, but some indices were not reproducible in nonobese healthy controls. When results were analyzed in the study population as a whole, all indices were reproducible. CONCLUSIONS: In this study, although reproducibility was noted for all IR indices in obese subjects, reproducibility was not observed for some of the indices in nonobese women. Reasons for this finding may have been the small patient population of nonobese subjects or increased variability of the measures in low IR states. The observed reproducibility in the evaluation of the entire group supports the former reason, but studies with larger patient populations and different levels of IR are needed to confirm these results.en_US
dc.identifier.doi10.1016/S1499-2671(06)01001-Xen_US
dc.identifier.endpage51en_US
dc.identifier.issn1499-2671en_US
dc.identifier.issue1en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage46en_US
dc.identifier.urihttps://dx.doi.org/10.1016/S1499-2671(06)01001-X
dc.identifier.urihttps://hdl.handle.net/20.500.12395/20922
dc.identifier.volume30en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherCanadian Diabetes Associationen_US
dc.relation.ispartofCanadian Journal of Diabetesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectInsulin resistanceen_US
dc.subjectMeasurementen_US
dc.subjectObesityen_US
dc.subjectReproducibilityen_US
dc.titleReproducibility of fasting and OGTT-derived insulin resistance indices in normoglycemic womenen_US
dc.typeArticleen_US

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