Migren ve Helikobakter Pilori İlişkisi
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Dosyalar
Tarih
2005
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Helikobakter pilori (Hp) sıklıkla gastrit ve peptik ülser nedeni olmakla birlikte çeşitli hastalıklarla ilişkisi tartışılan bir mikroorganizmadır. Son zamanlarda migren ile Hp arasında ilişki olduğuna dair çeşitli yayınlar vardır. Bu çalışmada migren ile Hp birlikteliğinin anlamlı olup olmadığı araştırıldı. Yöntem: Selçuk Üniversitesi Meram Tıp Fakültesi Nöroloji Kliniği tarafından migren tanısı ile takip edilen 23 hasta ile kontrol grubu olarak gastroenteroloji kliniğine dispeptik şikayetlerle müracaat eden ve endoskopi planlanan 24 hasta çalışmaya dahil edildi. Çalışma ve kontrol grubunda, hem endoskopik biyopsi materyallerinde histolojik olarak, hem de hızlı üreaz testi (CLO test) ile Hp varlığı araştırıldı. Sonuçlar istatistiksel olarak değerlendirildi. Bulgular: Çalışma grubunda 19 hastada Hp () [% 82.6], 4 hastada Hp (-) [% 17.4] bulundu. Kontrol grubunda 6 hastada Hp () [% 25], 18 hastada Hp (-) [% 75] bulundu. Cinsiyet ve yaş farkı yoktu. Sonuç: Migrenli hastalarda Hp ()’liği kontrol grubuna göre anlamlı şekilde yüksek bulundu. Bu sonuç migren etyolojisinde Hp’nin rolünün daha geniş popülasyonlarda ve daha ileri yöntemlerle araştırılması gerektiğini ortaya koymuştur.
Objective: Migraine is a commonly unilateral, throbbing headache which has been associated with disorders of vascular tone. Hp the most relevant cause of gastritis and peptic ulcer. It has been also recently associated with a typical functional vascular disorders such as primary Reuynaud phenomenon. The aim of this study was to assess the prevalance of Hp in patients suffered from migraine. Methods: 23 patients with migraine who followed by Selcuk University Meram Faculty of Medicine Department of Neurology and 24 subjects as a control group were included to the study. Presence of Hp infection was diagnosed both with CLO (Campylobacter Like Organism) test and histological examination by carrying out endoscopy. Results: Hp was found positive in 19 of the migraine group (19/23, 82.6%) and in 6 of the control group (6/24, 25%). There was statistically significant difference between the groups (p<0.001). Conclusion: Hp positivity was found significantly higher in patients with migraine compared with control group. Provided data suggests that the role of chronic Hp infection in etiology of migraine should be investigated in more widely populations and with further developed methods.
Objective: Migraine is a commonly unilateral, throbbing headache which has been associated with disorders of vascular tone. Hp the most relevant cause of gastritis and peptic ulcer. It has been also recently associated with a typical functional vascular disorders such as primary Reuynaud phenomenon. The aim of this study was to assess the prevalance of Hp in patients suffered from migraine. Methods: 23 patients with migraine who followed by Selcuk University Meram Faculty of Medicine Department of Neurology and 24 subjects as a control group were included to the study. Presence of Hp infection was diagnosed both with CLO (Campylobacter Like Organism) test and histological examination by carrying out endoscopy. Results: Hp was found positive in 19 of the migraine group (19/23, 82.6%) and in 6 of the control group (6/24, 25%). There was statistically significant difference between the groups (p<0.001). Conclusion: Hp positivity was found significantly higher in patients with migraine compared with control group. Provided data suggests that the role of chronic Hp infection in etiology of migraine should be investigated in more widely populations and with further developed methods.
Açıklama
Anahtar Kelimeler
Genel ve Dahili Tıp, Migren, Helikobakter pilori, Migraine, Helicobacter pylori
Kaynak
Genel Tıp Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
15
Sayı
3
Künye
Polat, H., Demir, O., Güney, İ., Koçak, S., (2005). Migren ve Helikobakter Pilori İlişkisi. Genel Tıp Dergisi, 15(3), 107-109.
