Tip 1 diabetes mellituslu olgularda retina sinir lifi tabakasının değerlendirilmesi
Küçük Resim Yok
Tarih
2008
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Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Tip 1 Diabetes Mellitus (DM) tanısıyla izlenen ve retinopatisi bulunmayan olgularda Retina Sinir Lifi Tabakası (RSLT) kalınlık değişikliklerini optik koherens tomografi (OCT) kullanarak değerlendirmek. Gereç ve Yöntem: Oftalmolojik olarak görülebilen retinopati bulgusu ve oküler başka bir patolojisi bulunmayan 37 Tip 1 DM’li olgunun gözünden Stratus OCT kullanılarak alınan RSLT kalınlık ölçümleri, OCT cihazının normatif veri tabanı ve kontrol grubu ile karşılaştırıldı. Bulgular: Toplam 37 olgunun 15’i kadın 22’si erkek, yaş ortalaması 28,156,23 yıl idi. Yirmi kadın 29 erkek bulunan kontrol grubunun yaş ortalaması 28,385,72 yıl idi. Olguların RSLT kalınlığı süperior kadranda 119,61?, inferior kadranda 132,23?, nazal kadranda 76,77? ve temporal kadranda 69,42? olarak saptandı. Ortalama RSLT kalınlığı ise 99,93? idi. Kontrol grubunun RSLT kalınlığı ise süperior kadranda 123,47?, inferior kadranda 132,12?, nazal kadranda 79,53? ve temporal kadranda 72,05? olarak saptandı. Ortalama RSLT kalınlığı ise 101,77? idi. Tüm RSLT değerleri açısından gruplar arasında istatistiksel olarak anlamlı farklılık tespit edilmedi (sırasıyla p0,408, p0,679, p892, p0,711 ve p0,967). Olguların RSLT kalınlık değerleri OCT cihazının normatif veri tabanı ile kıyaslandığında, süperior kadranın 12, inferior kadranın 5, nazal kadranın 9, temporal kadranın 5 ve ortalama RSLT kalınlığının 5 gözde normal popülasyonun %95’inden ince olduğu saptandı. Sonuçlar: Çalışmamızda olgu sayısı az olmakla birlikte RSLT kalınlığının özellikle süperior kadranda normal popülasyona göre daha ince olması diabetik retinopatinin erken bulgularından biri olabileceğini düşündürmektedir
Aim: To evaluate the retinal nerve fiber layer thickness (RNFL) changes with Optical Coherence Tomography (OCT) in type 1 Diabetes Mellitus (DM) patients without retinopathy. Material and Method: Seventy four eyes of 37 patients with type 1 DM without retinopathy or other ocular and systemic disease were enrolled in the study. RNFL thickness measurements obtained from OCT were compared with normative database of the OCT device and control group. Results: A total of 37 patients, 22 male and 15 female, with a mean age of 28.15±6.23 years met our inclusion criteria. The mean age of subjects, 29 male and 20 female, in the control group was 28.38±5.72 years. RNFL thicknesses in the superior, inferior, nasal and temporal quadrants were 119.61μ, 132.23μ, 76.77μ and 69.42μ, respectively. The mean RNFL thickness was 99.93μ. In control group, the RNFL thicknesses in the superior, inferior, nasal and temporal quadrants were 123.47μ, 132.12μ, 79.53μ and 72.05μ, respectively. The mean RNFL thickness of the control group was 101.77μ. There was no statistically significant difference between groups with respect to RNFL thickness values (p0.408, p0.679, p892, p0.711 and p0.967, respectively). The mean RNFL thickness, superior, inferior, nasal and temporal quadrant thickness were lower than 95% of normal population in 5, 12, 5, 9 and 5 patients respectively, compared with normative database of the OCT device. Conclusion: Despite the limited number of cases included in our study, the thinning of RNFL in type 1 DM patients without retinopathy especially in the superior quadrant was remarkable suggesting a preceeding finding of retinopathy
Aim: To evaluate the retinal nerve fiber layer thickness (RNFL) changes with Optical Coherence Tomography (OCT) in type 1 Diabetes Mellitus (DM) patients without retinopathy. Material and Method: Seventy four eyes of 37 patients with type 1 DM without retinopathy or other ocular and systemic disease were enrolled in the study. RNFL thickness measurements obtained from OCT were compared with normative database of the OCT device and control group. Results: A total of 37 patients, 22 male and 15 female, with a mean age of 28.15±6.23 years met our inclusion criteria. The mean age of subjects, 29 male and 20 female, in the control group was 28.38±5.72 years. RNFL thicknesses in the superior, inferior, nasal and temporal quadrants were 119.61μ, 132.23μ, 76.77μ and 69.42μ, respectively. The mean RNFL thickness was 99.93μ. In control group, the RNFL thicknesses in the superior, inferior, nasal and temporal quadrants were 123.47μ, 132.12μ, 79.53μ and 72.05μ, respectively. The mean RNFL thickness of the control group was 101.77μ. There was no statistically significant difference between groups with respect to RNFL thickness values (p0.408, p0.679, p892, p0.711 and p0.967, respectively). The mean RNFL thickness, superior, inferior, nasal and temporal quadrant thickness were lower than 95% of normal population in 5, 12, 5, 9 and 5 patients respectively, compared with normative database of the OCT device. Conclusion: Despite the limited number of cases included in our study, the thinning of RNFL in type 1 DM patients without retinopathy especially in the superior quadrant was remarkable suggesting a preceeding finding of retinopathy
Açıklama
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Kaynak
MN Oftalmoloji
WoS Q Değeri
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Cilt
15
Sayı
4